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Jyotirmayee Dash

IIT, Kanpur (2003)
Area of Interest:
Organic Chemistry, Nucleic Acid Chemistry
Email ID:
Research Interest:

We are interested in synthesis of natural and non-natural synthetic targets that can find wide ranging application spanning from chemical biology to material science. Our ongoing research projects focus on (i) diversity oriented synthesis, (ii) organocatalytic transformation, (iii) bio-inspired molecular and supramolecular assemblies and (iv) small molecule-nucleic acid recognition.

Academic Qualification:
  • Ph.D. (Synthetic Organic Chemistry), Indian Institute of Technology, Kanpur, India, 2003.
  • M.Sc. (Chemistry), Ravenshaw University, Cuttack, India, 1997.
  • Assistant Professor, Indian Institute of Science Education and Research (IISER), Kolkata, 2009 -.
Awards and Honors:
  • Visiting Fellow, May-July 2010, University of Bristol, UK.
  • Marie-Curie International Incoming Postdoctoral Fellow, 2007-2009, University of Cambridge, UK.
  • Postdoctoral Research Fellow, 2006-2007, ESPCI-Paris, France.
  • Alexander von Humboldt Fellow, 2004-2006, Freie Universität Berlin, Germany.



List of Publications:
  1. Diffusion and Birefrengence of Bioactive Dyes in a Guanosine Supramolecular Hydrogel  R. N. Das, Y. P. Kumar, S. Pagoti, A. J. Patil, J. Dash, Chem. Eur. J. 2012, DOI: 10.1002/chem.201103814.
  2. Synthesis of Bis-indole Carboxamides as G-quadruplex Stabilizing and Inducing Ligands J. Dash, R. N. Das, N. Hegde, G. D. Pantoș, P. S. Shirude, S. Balasubramanian, Chem. Eur. J. 2012, 18, 554-564.
  3. A supported palladium nanocatalyst for copper free acyl Sonogashira reactions: One-pot multicomponent synthesis of N-containing heterocycles, S. Santra, K. Dhara, P. Ranjan, P. Bera, J. Dash, S. Mandal, Green Chemistry, 2011, 13, 3238-3247.
  4. Modulation of small molecule induced architecture of cyclodextrin aggregation by guest structure and host size, P. Ghosh, A. Maity, T. Das, J. Dash, P. Purkayastha, J. Phys. Chem. C, 2011, 115, 20970–20977.
  5. Interaction of a new surface sensitive probe compound with anionic surfactants of varying hydrophobic chain length, A. Maity, P. Ghosh, T. Das, J. Dash, P. Purkayastha, J. Colloids Interface Sci. 2011, 364, 395-399.
  6. Supramolecular hydrogels derived from silver ion-mediated self-assembly of 5'-guanosine monophosphate, J. Dash, A. J. Patil, R. N. Das, F. L. Dowdall, S. Mann, Soft Matter, 2011, 7, 8120-8126.
  7. Iron Catalyzed Highly Regioselective Dimerization of Terminal Aryl Alkynes, G. C. Midya, S. Paladhi, K. Dhara, J. Dash, Chem. Commun. 2011, 47, 6698-6700.
  8. Synthesis of Spirocyclic Thiazolidinedione Derivatives Using Ring-Closing Metathesis and One-Pot Sequential Ring-Closing/Cross Metathesis” K. Dhara, S. Paladhi, G. C. Midya, J. Dash, Org. Biomol. Chem. 2011, 9, 3801-3807.
  9. Synthesis and Binding Studies of Novel Diethynyl-pyridine Amides with Genomic Promoter DNA G-quadruplexes, J. Dash, Z. A. E. Waller, G. Dan Pantos, S. Balasubramanian, Chem Eur. J. 2011, 17,  4571-4581.
  10. G-quadruplex-binding benzo[a]phenoxazines down-regulate c-KIT expression in human gastric carcinoma cells, K. I. E. McLuckie, Z. A. E. Waller,  D. A. Sanders, D. Alves, R. Rodriguez,  J. Dash, G. J. McKenzie, A. R. Venkitaraman, S. Balasubramanian, J. Am. Chem. Soc. 2011, 133, 2658-2663.
  11. A Concise Approach towards the Synthesis of WS75624 A and WS75624 B via the crossmetathesis of vinyl-functionalized thiazoles, J. Dash, B. Melillo, S. Arseniyadis, J. Cossy, Tetrahedron Lett. 2011, 52, 2246-2249. (Published in honour of Professor Harry H. Wasserman on the occasion of his 90th birthday)
  12. A three-component synthesis of -alkoxy--keto-enamides—flexible precursors for 4-hydroxypyridine derivatives and their palladium-catalysed reactions,T. Lechel, J. Dash, C. Eidamshausa, I. Brüdgam, D. Lentza, H.-U. Reissig, Org. Biomol. Chem. 2010, 8, 3007-3014.
  13. Three-Component Synthesis of Perfluoroalkyl- or Perfluoroaryl-Substituted 4-Hydroxypyridine Derivatives and Their Palladium-Catalyzed Coupling Reactions; T. Lechel, J. Dash, P. Hommes, D. Lentz, H.-U. Reissig, J. Org. Chem. 2010, 75, 726–732.
  14. A New and Flexible Synthesis of 4-Hydroxypyridines: Rapid Access to Caerulomycins A, E and Functionalized Terpyridines; J. Dash, H.-U. Reissig, Chem. Eur. J. 2009, 15, 6811-6814.
  15. Enantioselective Organocatalytic Conjugate Reduction of β-Azole α,β‑Unsaturated Aldehydes; T. J. Hoffman, J. Dash, J. H. Rigby, S. Arseniyadis and J. Cossy, Org. Lett. 2009, 11, 2756-2759.
  16. Diarylethynyl Amides That Recognize the Parallel Conformation of Genomic Promoter DNA G-quadruplexes; J. Dash, P.S. Shirude, S.-T.D. Hsu, S. Balasubramanian, J. Am. Chem. Soc. 2008, 130, 15950–15956.
  17. G-Quadruplex Recognition by Bis-indole Carboxamides; J. Dash, P.S. Shirude, S. Balasubramanian, Chem. Commun. 2008, 3055–3057.
  18. Novel Furopyridine Derivatives via Sonogashira Reactions of Functionalized Pyridines; T. Lechel, J. Dash, I. Brüdgam, H.-U. Reissig, Eur. J. Org. Chem. 2008, 3647–3655.
  19. Crystal Structure of 1,4-bis[3-methoxy-4-(4-methoxyphenyl)-6-(trifluoromethyl)pyridin-2yl]benzene, C34H26F6N2O4; J. Dash, I. Brüdgam, H. Hartl, H.-U. Reissig, Z. Kristallogr. NCS 2008, 223, 347–348.
  20. Synthesis of Vinyl-Functionalized Thiazoles by Cross-Metathesis and Tandem Stille Coupling/Cross-Metathesis; J. Dash, S. Arseniyadis, J. Cossy, Adv. Synth. Catal. 2007, 349, 152–156.
  21. Scope of a Novel Three-Component Synthesis of Highly Functionalized Pyridines; J. Dash, T. Lechel, H.-U. Reissig, Org. Lett. 2007, 9, 5541–5544.
  22. A Concise Synthesis of Novel Oxa-bridged Compounds; F.A. Khan, J. Dash, Ch. Sudheer, N. Sahu, P. Karuppasamy; J. Org. Chem. 2005, 70, 7565–7577.
  23. A New Color of the Synthetic Chameleon Methoxyallene: A Novel Synthesis of Trifluoromethyl-Substituted Pyridinol Derivatives–An Unusual Reaction Mechanism, A Remarkable Crystal Packing, and First Palladium-Catalyzed Coupling Reactions; O. Flögel, J. Dash, I. Brüdgam, H. Hartl, H.-U. Reissig, Chem. Eur. J. 2004, 10, 4283–4290.
  24. Hydrotalcite Catalysis in Ionic Liquid Medium: A Recyclable Reaction System for Heterogeneous Knoevenagel and Nitroaldol Condensation; F.A. Khan, J. Dash, R. Satapathy, S.K. Upadhyay, Tetrahedron Lett. 2004, 45, 3055–3058.
  25. Indium-Mediated Regio- and Diastereoselective Reduction of Norbornyl α-Diketones; F.A. Khan, J. Dash, Ch. Sudheer, Chem. Eur. J. 2004, 10, 2507–2519.
  26. Diastereoselection During Allylindium Addition to Norbornyl α-Diketones; F.A. Khan, J. Dash, Eur. J. Org. Chem. 2004, 2692–2700.
  27. A Rapid and Stereoselective Route to trans-Hydrindane Ring System; F.A. Khan, R. Satapathy, J. Dash, G. Savitha, J. Org. Chem. 2004, 69, 5295–5301.
  28. A Short and Stereoselective Synthesis of Functionalized Pentenomycin Derivatives; F.A. Khan, J. Dash and B. Rout, Tetrahedron Lett. 2004, 45, 9285–9288.
  29. A Novel and Expeditious Approach to Unusual Spiro Lactam Building Blocks; F. A. Khan, J. Dash, J. Org. Chem. 2003, 68, 4556–4559.
  30. Chemoselective Reduction of Aromatic Nitro and Azo Compounds in Ionic Liquids Using Zinc and Ammonium salts; F.A. Khan, J. Dash, Ch. Sudheer, R.K. Gupta, Tetrahedron Lett. 2003, 44, 7783–7789.
  31. An Easy Access to γ-Lactone-fused Cyclopentanoids; F.A. Khan, J. Dash, N. Sahu, Ch. Sudheer, J. Org. Chem. 2002, 67, 3783–3787.
  32. Regio- and Diastereoselective Reduction of Non-enolizable α-Diketones to Acyloins Mediated by Indium Metal; F. A. Khan, J. Dash, N. Sahu, S. Gupta, Org. Lett. 2002, 4, 1015–1018.
  33. Synthesis of a Novel, Highly Symmetric Bis-Oxa-Bridged Compound; F.A. Khan, J. Dash, J. Am. Chem. Soc. 2002, 124, 2424–2425.
  34. Synthesis of Novel Caged Bishemiacetals and their Facile Conversion to Symmetric Bis-α-halo-γ-lactones; F.A. Khan, N. Sahu, J. Dash, and B. Prabhudas, J. Ind. Inst. Sciences 2001, 81, 325–331.
  35. Rearrangement of 1,4,5,6-Tetrahalo-7,7-dimethoxybicyclo[2.2.1]hept-5-ene-2-one to Phenolic Derivatives; F.A. Khan, J. Dash, D. Jain, and B. Prabhudas, J. Chem. Soc., Perkin Trans. 1, 2001, 3132–3134.
  36. 1,2,3,4-Tetrachloro-5,5-dimethoxy-cyclopenta-1,3-diene: Diels-Alder Reactions and Applications of the Products Formed; F.A. Khan, B. Prabhudas, J. Dash, J. Prakt. Chem. 2000, 342, 512–517.
  37. A Ruthenium Catalyzed, Novel and Facile Procedure for the Conversion of Vicinal Dihaloalkenes to α-Diketones; F.A. Khan, B. Prabhudas, J. Dash, N. Sahu, J. Am. Chem. Soc. 2000, 122, 9558–9559.