Arindam Mukherjee

Associate Professor
Dept: Chemical Sciences (DCS)
E-mail: a.mukherjee [at] iiserkol.ac.in
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Research Interest:

    The research group is interested in the magneto-structural and chemical properties of multiple and single transition metal based co-ordination complexes using sterically hindered (viz. bulky amine and imine based ligands) and/or redox non-innocent planar ligands (viz. 9-hydroxyphenalenone derivatives). The obtained complexes are explored for their magneto-structural properties and catalysis. Tuning the redox properties and activities of metal ions are performed with designed ligands without overlooking the possibilities of such ligands or their derivatives themselves to be potent against cancer. Complexes of expected potency are tested for antiucancer and antileishmania activity.Heterocycles of interest are synthesized using catalytic and non-catalytic pathways. Nitrogen mustards and nitrosoureas which would be better soluble and more active in hypoxic conditions are synthesized and studied. Our newest playground is the betalactams as anti-Dyslipidemia agents. The students perform the syntheses, characterization including single crystal XRD, ESI MS and NMR all by themselves. The lab has a clean room to test cytotoxicity on human cancer cell lines, and certain E.coli strains for necessary protein syntheses by the group members.


Academic Background:
  1. Ph.D. in chemical sciences (magneto-structural corelation), Indian Institute of Science, 2005, Best thesis award by IISc


Positions:
  1. Research Fellow, University of Melbourne (2005 - 2006)
  2. Marie Curie Fellow, University of Edinburgh (2006 - 2007)
  3. Marie Curie Fellow, University of Warwick (2007 - 2008)
  4. RDF Strategic fellow and investigator, University of Warwick (2008 - 2009)
  5. Assistant Professor, IISER Kolkata (2009 - 2013)
  6. Associate Professor, IISER Kolkata ( - )


Awards and Honors:
  1. Surendranath Bhattacharyya Medal from University of North Bengal (1999)
  2. IRCSET Fellowship from Ireland Council of Science Engeneering and Technology (2006)
  3. Marie Curie Fellowship from European Commission (2006)
  4. RDF strategic award from University of Wawick (2008)


Selected Publications:
  1. Purkait, Kallol; Karmakar, Subhendu; Bhattacharyya, Sudipta; Chatterjee, Saprtarshi and Mukherjee*, Arindam. 2015. "A hypoxia efficient imidazole-based Ru(II) arene anticancer agent resistant to deactivation by glutathione." Dalton Trans., 44, 5969-73
  2. Sarkar, Amrita; Karmakar, Subhendu; Bhattacharyya, Sudipta; Purkait, Kallol and Mukherjee*, Arindam. 2015. "Nitric oxide release by N-(2-chloroethyl)-N-nitrosoureas: a rarely discussed mechanistic path towards their anticancer activity." RSC Advances, 5, 2137-46
  3. Dey, Suman Kr; Mitra, Partha and Mukherjee*, Arindam. 2015. "Influence of Solvent in Solvothermal Syntheses: Change of Nuclearity in Mixed Valence CoII/III Complexes of a O‑Donor-rich Schiff Base Ligand." Cryst. Growth Des, 15, 706-17