Details of LS4203 (Spring 2013)

Level: 4 Type: Theory Credits: 3.0

Course CodeCourse NameInstructor(s)
LS4203 Systems Biology Anandamohan Ghosh,
Anirban Banerjee

Syllabus
Partho Sarathi Roy [3 lectures]:
Introduction to Systems Biology
Gene Regulation
Basic concepts of network

Anirban Banerjee [~6-9 lectures]:
Heuristic parameters (deg distbn,z-score...)
Network motifs
Autoregulation - FFL
Structural robustness
Types of network model (scale free, small world....)

Anandamohan Ghosh [~24-27 lectures]:
Dynamical systems basic concepts
Oscillations - lambda phage
Reaction kinetics - Michaelis Menten - Hill equation (transcription network)
Stochastic process
Robustness - chemotaxis
Optimality in gene circuit design
Population dynamics - pattern formation in reaction diffusion systems

References
1. An Introduction to Systems Biology: Design Principles of Biological Circuits - Uri Alon Chapman & Hall/CRC Mathematical & Computational Biology.
2. Nonlinear Dynamics and Chaos: With Applications To Physics, Biology, Chemistry, and Engineering - Steven Strogatz; Westview Press.
3. Mathematical Biology I and II (3rd Edition) - J.D. Murray; Springer

Course Credit Options

Sl. No.ProgrammeSemester NoCourse Choice
1 IP 2 Not Allowed
2 IP 4 Elective
3 MS 8 Elective
4 RS 1 Elective