- Structure and Bonding in Organic Compounds: Basic bonding concepts, Modern theory of orbital mixing, Qualitative molecular orbital theory, Building simple organic molecules using group orbitals, Bonding and structure of reactive intermediates.
- Strain and Stability: Thermochemistry of stable molecules and reactive intermediates, Relationship between structure and energetic, Basic conformational analysis, Electronic effects, Highly strained molecules.
- Reaction Stereochemistry: A quick look at molecular symmetry, Stereoselectivity and stereospecificity, Topological and supramolecular stereochemistry, Stereoelectronic effects in organic chemistry, Orbital interaction rules, Geometric restriction of the orbital overlap, Stereoelectronic effects on conformations, Anomeric effect, Stereoelectronic effects on reactivity, Effects through chemical bonds and through space, Stereochemical issues in polymer chemistry, Stereochemical issues in chemical biology.
- Pericyclic Reactions: Concepts from electronic structure theory, Results from HMO theory, Perturbation theory, Orbital mixing rules, Organic chemistry and MO theory, Several useful reactions: Cycloadditions, Sigmatropic rearrangements, Electrocylcic reactions, Chelotropic reactions, Practice problems in pericyclic reactions.
- Organic Photochemistry: Principles of photochemistry, Grotthuss-Draper law, Stark-Einstein law, Franck-Condon Principle, Several useful reactions: Free radical reactions, Electrocyclic reactions, Photoisomerization, Norrish reactions; Practice problems in photochemical reactions.
- Noncovalent Interactions and Ssupramolecular Chemistry: Solutions; influence of reaction media in organic chemistry; types of noncovalent binding forces; origin of hydrogen bonding and molecular recognition; origin of hydrophobic effect; hydrogen bonds in proteins.
|