Details of CH4202 (Spring 2019)
Level: 4 | Type: Theory | Credits: 4.0 |
Course Code | Course Name | Instructor(s) |
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CH4202 | Natural Products and Medicinal Chemistry | Balaram Mukhopadhyay, Dibyendu Das |
Syllabus |
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Carbohydrates: Carbohydrate nomenclature, structures, anomeric effect: principles and applications, mutarotation, functional group modifications, glycosylations, biological importance of carbohydrates, enzymatic glycosylations, vaccine design. Proteins and Amino Acids: alpha-Amino Acids, other amino acids and their importance, isoelectric point, preparation of amino acids, reactions of AA, peptide bond formation, reagents-reactions, solid phase peptide synthesis, peptides and proteins. Lipids, terpenoids, prostaglandins, steroids, polyketides: Fatty Acids: Saturated, unsaturated (nomenclature), roles in biological processes, detergents, Fats & Oils, Phospholipids, cellular membrane. Prostaglandins; Terpenes; Steroids; Polyketides: Synthesis and Biosynthetic Mechanisms; Alkaloids: Classification, Indole alkaloids (the largest class of the alkaloids) Synthesis of some alkaloids: Mannich, Pictet-Spengler, and Bischler-Napieralski reactions; Dyes: Roles in plants and animals. Classifications: Indigoid, anthraquinonoid, flavonoids, dihydropyranoids, carotenoids, etc.
Introduction to Medicinal Chemistry Biopharmaceutical Properties of Drug Substances Pharmacologic Activity Drug Design Drug/Receptor Interactions Drug Resistance and Metabolism Metal-Based Drugs |
References |
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Course Credit Options
Sl. No. | Programme | Semester No | Course Choice |
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1 | IP | 2 | Not Allowed |
2 | IP | 4 | Core |
3 | IP | 6 | Not Allowed |
4 | MR | 2 | Not Allowed |
5 | MR | 4 | Not Allowed |
6 | MS | 8 | Core |
7 | RS | 1 | Elective |
8 | RS | 2 | Elective |