- Concepts:
- Essential mathematical tools; Concepts of heat, work, entropy, free energy minimization; Boltzmann Distribution
- Revision of random walk, Persistence length
- Fluctuations, Diffusion and Dissipation.
- Non-bonded interactions, Bjerrum length, Debye screening, Poisson-Boltzmann Equation;
- Nonequilibrium distribution of ions in cells: Donnan Equilibrium, Nernst Potential;
- Macroscopic manifestation: Reynolds Number, Naviers Stokes Equation;
- Stochastic processes.
- Systems/processes from different scales:
- Forces and energetics of Protein structure and folding; Allosteric interactions;
- Membrane structure and mechanics;
- Forces generated by actin polymerization, molecular motors;
- Mechanisms of origin and propagation of action potential;
- Mechanism of bacterial motility, understanding blood flow through capillaries;
- Pattern formation and oscillations in biosystems.
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