Probably, the answer to the question, how is organismal complexity encoded by genomes, lies not in number of genes in an organism, rather in the regulation of gene expression including that by small-RNAs (smRNAs). Much is understood about smRNA biogenesis; on the exploration of functions of small-RNAs in regulating different biological networks including those of cellular signaling, we have just begun.
Identifying functional roles of smRNA-based regulation at the level of specific tissues and whole organisms is crucially needed for a more integrative understanding of how RNA-silencing functions in cellular and ecological contexts. In our group, we explore this question by combining systems biology, next-generation deep sequencing and experimental approaches.
Various questions that we are dealing with are specifically as follows:
1. The role of small-RNA pathways in plant stress adaptations.
2. Understanding conceptual parallels between eukaryotic and prokaryotic small-RNA pathways.
3. Molecular basis of wheat-spot blotch (plant-pathogen) interaction.
4. Non-host resistance in wheat and rice.
Our Research focus!
We use a combination of experimental and computational approaches of
Next Generation Sequencing, Bioinformatics & Genomics,Plant Molecular Biology, Ecology & Field Biology, Other Omics Approaches, Analytical Chemistry
Shree P. Pandey
Head of MPG-India Partner Group
Education & Training
Post Doc: Massachusetts Institute of Technology, USA; Max Planck Institute for Plant Breeding, Germany
PhD: Max Planck Institute for Chemical Ecology, and FSU, Jena, Germany
APGD in Bioinformatics, Jawaharlal Nehru University, New Delhi, India
BSc (Ag) & MSc (Ag) Banaras Hindu University, Varanasi, India
C-10, Prefab-III, IISER-Kolkata, Mohanpur, Nadia-741246
Collaborator's Field station: Cooch Behar, RAU Ranchi, BHU Varanasi
Shree Prakash Pandey, Indian Institute of Science Education Research (IISER) Kolkata, Mohanpur Campus, Mohanpur - 741246, India
Lab contact: +918450073727