Details of CH3202 (Spring 2013)
| Level: 3 | Type: Theory | Credits: 3.0 |
| Course Code | Course Name | Instructor(s) |
|---|---|---|
| CH3202 | Physical Organic and Organic Chemistry | Chilla Malla Reddy |
| Syllabus |
|---|
| Structure and bonding in organic compounds: Basic bonding concepts; Modern theory of orbital mixing, qualitative molecular orbital theory; building simple organic molecules using group orbitals; bonding and structure of reactive intermediates.
Strain and stability: Thermochemistry of stable molecules and reactive intermediates; relationship between structure and energetics; basic conformational analysis; electronic effects; highly strained molecules. Reaction Stereochemistry: A quick look at molecular symmetry; Stereoselectivity and stereospecificity; topological and supramolecular stereochemistry; stereoelectronic effects in organic chemistry; orbital interaction rules; geometric restriction of the orbital overlap; stereoelectronic effects on conformations; anomeric effect; stereoelectronic effects on reactivity; effects through chemical bonds and through space; stereochemical issues in polymer chemistry; stereochemical issues in chemical biology. Pericyclic reactions: Concepts from electronic structure theory; results from HMO theory; perturbation theory; orbital mixing rules; organic chemistry and MO theory; Several useful reactions: Cycloadditions, sigmatropic rearrangements, electrocylcic reactions, chelotropic reactions; Practice problems in pericyclic reactions. Organic photochemistry: Principles of photochemistry; Grotthuss-Draper law; Stark-Einstein law; Franck-Condon Principle; Several useful reactions: Free radical reactions, electrocyclic reactions, photoisomerization, Norrish reactions etc.; Practice problems in photochemical reactions. Noncovalent interactions and supramolecular chemistry: Solutions; influence of reaction media in organic chemistry; types of noncovalent binding forces; origin of hydrogen bonding and molecular recognition; origin of hydrophobic effect; hydrogen bonds in proteins. |
| References |
|---|
| 1. E. V. Anslyn and D. A. Dougherty, Modern Physical Organic Chemistry, University Science Books (2004).
2. F. C. Carey and K. Sundberg, Advanced Organic Chemistry, Part A and B, Springer Science and Business Media, Berlin (2007). 3. I. Fleming, Frontier Orbitals: Organic Chemical Reactions, John Wiley, New York (1976). 4. M. B. Smith and J. March, Marchs Advanced Organic Chemistry: Reactions Mechanism & Strcture (5th Edition), John Wiley, New York. 5. A. Gilbert and J. Baggott, "Essentials of Molecular Photochemistry," CRC Press, London, UK, 1991. |
Course Credit Options
| Sl. No. | Programme | Semester No | Course Choice |
|---|---|---|---|
| 1 | IP | 2 | Core |
| 2 | IP | 4 | Not Allowed |
| 3 | MS | 6 | Core |
| 4 | RS | 1 | Elective |