Details of CH4202 (Spring 2014)

Level: 4 Type: Theory Credits: 3.0

Course CodeCourse NameInstructor(s)
CH4202 Chemistry of Natural Products Balaram Mukhopadhyay,
Sanjio S. Zade

Preamble
This is a specialized course that describes the chemical aspects of various natural products.

Syllabus


  • Carbohydrates: Carbohydrate nomenclature, structures, anomeric effect: principles and applications, mutarotation, functional group modifications, glycosylations, biological importance of carbohydrates, enzymatic glycosylations, vaccine design.

  • Proteins and Amino Acids: $\alpha $-Amino Acids, Other amino acids and their importance, isoelectric point, preparation of amino acids, reactions of AA, peptide bond formation, reagents-reactions, solid phase peptide synthesis, peptides and proteins.

  • Lipids, terpenoids, prostaglandins, steroids, polyketides: Fatty Acids: Saturated, unsaturated (nomenclature), roles in biological processes, detergents, Fats & Oils, Phospholipids, cellular membrane

    Prostaglandins; Terpenes; Steroids; Polyketides: Synthesis and Biosynthetic Mechanisms.

  • Alkaloids: Classification, Indole alkaloids (the largest class of the alkaloids) Synthesis of some alkaloids: Mannich, Pictet-Spengler, and Bischler-Napieralski reactions.

  • Dyes: Roles in plants and animals, classifications: Indigoid, anthraquinonoid, flavonoids, dihydropyranoids, carotenoids, etc.: Synthesis.


References


  1. Handbook of Heterocyclic Chemistry 2nd Edition by A. R. Katritzky, A. F. Pozharski, Pergamon/Elsevier, (2000).

  2. Heterocyclic Chemistry, 5th Ed. by J. A. Joule, K. Mills.

  3. Organic Chemistry by Jonathan Clayden, Nick Greeves, Stuart Warren and Peter Wothers.

  4. Organic Chemistry, vol.1 and 2, 4th edition by I.L. Finar, Longmans.


Course Credit Options

Sl. No.ProgrammeSemester NoCourse Choice
1 IP 2 Not Allowed
2 IP 4 Core
3 MR 2 Not Allowed
4 MR 4 Not Allowed
5 MS 8 Core
6 RS 1 Elective
7 RS 2 Not Allowed