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Details of LS4207 (Spring 2015)

Level: 4 Type: Theory Credits: 3.0

Course CodeCourse NameInstructor(s)
LS4207 Applied and Clinical Biochemistry Rituparna Sinha Roy,
Supratim Datta

Preamble
This course designed to provide undergraduate students with an introduction to how nature transforms and manipulate biologically relevant molecules. We will start by introducing the fundamentals of enzyme-catalyzed reactions, especially as they apply to large-scale production of small molecules. Examples on how proteins are engineered will be discussed through lectures and student presentations. The last month (~10 lectures) of the course will focus on designing therapeutic biomolecules and nanobiotechnology

Syllabus


  • Protein Structure:
    Protein structure and Biocatalysis
  • Protein Engineering: Methods of engineering proteins; Applications of protein engineering.

  • Clinical Biochemistry:Therapeutic Biomolecules; Bioconjugation Techniques for Biomedical Sciences; Introduction and functionalization of nanostructures and Nanoparticle based therapies



Prerequisite
A basic knowledge of Biochemistry will be assumed

References


  1. Carl-Ivar Brndn, John Tooze, Introduction to Protein Structure, Garland Publishing, (1999)

  2. Sheldon J. Park, Jennifer R. Cochran, Protein Engineering and Design, CRC Press (2010).

  3. Wittrup KD, Verdine GL, Protein Engineering for Therapeutics , Narosa (2008).

  4. Kewal K. Jain, The Handbook of Nanomedicine , Tata McGraw Hill (2009)


Course Credit Options

Sl. No.ProgrammeSemester NoCourse Choice
1 IP 2 Elective
2 IP 4 Elective
3 MR 2 Not Allowed
4 MR 4 Not Allowed
5 MS 8 Elective
6 RS 1 Elective
7 RS 2 Elective

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