WeLearn :: Academic Portal of IISER Kolkata

Page path

Details of LS4205 (Spring 2016)

Level: 4 Type: Theory Credits: 3.0

Course CodeCourse NameInstructor(s)
LS4205 Applied Biochemistry Supratim Datta

Preamble
This course designed to provide undergraduate students with an introduction to how nature transforms and manipulate biologically relevant molecules. We will start by introducing the fundamentals of enzyme-catalyzed reactions, especially as they apply to large-scale production of small molecules. Examples on how proteins are engineered will be discussed through lectures and student presentations.

Syllabus


  • Protein Structure:
    Protein structure and Biocatalysis; Protein Structure visualization; Recombinant DNA tools;
  • Protein Engineering: Methods of engineering proteins; High-throughput Assays;Role of scaffolds; Phage Display; Circular Permutation; Computation and de novo protein design;
  • Applications of Protein Engineering: Antibody Engineering; Therapeutics; Biosimilars; Biomaterials


References


  1. Carl-Ivar Brndn, John Tooze, Introduction to Protein Structure, Garland Publishing, (1999)

  2. Sheldon J. Park, Jennifer R. Cochran, Protein Engineering and Design, CRC Press (2010).


Course Credit Options

Sl. No.ProgrammeSemester NoCourse Choice
1 IP 2 Elective
2 IP 4 Elective
3 IP 6 Not Allowed
4 MR 2 Not Allowed
5 MR 4 Not Allowed
6 MS 8 Elective
7 RS 1 Elective
8 RS 2 Elective

Home