Details of LS3203 (Spring 2017)

Level: 3 Type: Theory Credits: 3.0

Course CodeCourse NameInstructor(s)
LS3203 Biophysics II Bidisha Sinha


  • Probability distributions, ideal gas law, Boltzmann Distribution
  • Random walk, friction, Diffusion. Impact on biological processes.
  • Revision of entropy, temperature, free energy
  • Protein-DNA interactions, electrostatic interactions, Debye screening, role in chromatin deformability and packing. Kinetics of repressor-DNA interaction.
  • Aqueous, Ionic equilibrium of a living cell, osmotic pressure, non-equilibrium distributions of ions. Ion transport in membranes, physical basis of action potential creation and propagation. Introduction to Cable equation.
  • Self assembly in cells. Cooperative transitions.
  • Membrane mechanics, membrane deformation by protein-membrane interactions.
  • Biophysical characteristics of a tissue: Surface and interfacial tensions.
  • Biophysics of cancer.


  1. Biological Physics (updated edition, 2004) Philip C. Nelson.
  2. Biophysics. Roland Glasser. Springer (2001)
  3. Random walks in biology. H. Berg. Princeton University Press (1993)
  4. Molecular Biology of the cell. Alberts et al. Garland Science (2007)
  5. Physical Biology of the cell. Rob Phillips, Jane Kondev, Julie Theriot. Garland Science (2008)

Course Credit Options

Sl. No.ProgrammeSemester NoCourse Choice
1 IP 2 Core
2 IP 4 Elective
3 IP 6 Not Allowed
4 MR 2 Not Allowed
5 MR 4 Not Allowed
6 MS 6 Core
7 RS 1 Elective
8 RS 2 Elective