Details of CH3106 (Autumn 2018)

Level: 5 Type: Theory Credits: 4.0

Course CodeCourse NameInstructor(s)
CH3106 Supramolecular Chemistry Chilla Malla Reddy,
Debasish Haldar,
Rahul Banerjee

Syllabus
Basic concept and principles; History, Molecular recognition, Hydrogen Bonds: Definition, Structure and Stability, strength, Secondary Electrostatic Interactions in Hydrogen Bonding Arrays

Non-covalent interactions: Ion pairing, Ion-Dipole Interactions, Dipole-Dipole interactions, Dipole-Induced Dipole and Ion-Induced Dipole interactions,van der Waals or Dispersion Interactions, Hydrogen bonding, Halogen bonding, Cation- interactions, Anion-pi interactions, pi - pi interactions, Closed shell interactions, Aromatic-Aromatic Interactions: Benzene Crystals, Edge-to-face vs. pi-pi Stacking Interactions, N-H- pi interactions, Sulfur-aromatic interactions, Benzene-Hexafluorobenzene pi-stacking.
Biological supramolecular systems: Ionophores, Porphyrin and other Tetrapyrrolic Macrocycles, Coenzymes, Neurotransmitters, DNA and Biochemical Self-assembly.
Supramolecular reactivity
Biomimetic systems and Artificial receptors:
(a) Cation Binding Hosts - Podand, Crown Ether, Cryptand, Spherand; Nomenclature, Selectivity and Solution Behaviour; Alkalides, Electrides, Calixarenes and Siderophores.
(b) Anion binding hosts - Challenges and Concepts, Biological Receptors, Conversion of Cation Hosts to Anion Hosts, Neutral Receptors, Metal-Containing Receptors, Cholapods.
(c ) Ion Pair Receptors - Contact Ion Pairs, Cascade Complexes, Remote Anion and Cation Binding Sites, Symport and Metals Extraction.
(d) Hosts for Neutral Receptors -Clathrates, Inclusion Compounds, Zeolites, Intercalates, Coordination Polymers, Guest Binding by Cavitands and Cyclodextrins, cucurbituril.
Transport processes; Dynamic Combinatorial chemistry
Supramolecular chirality and chirality imprinting
Solid-State Chemistry
Organic Crystal Structures, Metal Organic Frameworks (MOFs), Covalent Organic Frameworks, Polymorphism, Solvates, Co-Crystals, Salts, Amarphous Materials
Crystal Engineering: Supramolecular Synthons, Structure-Property Correlation, Design of Solids, Design of Properties, phase transformations, stimuli responsive solids
Topochemical 2+2 cycloadditions in cinnamic acids under light
Topochemical photopolymerization in crystals

References
1. Supramolecular Chemistry by J. W. Steed & J. L. Atwood, 2ndEdn John Wiley, 2009.

2. Crystal Engineering. The Design of Organic Solids by G.R. Desiraju, Elsevier, 1989.

3. J. M. Lehn, Supramolecular Chemistry, VCH, Weinheim, 1995

Course Credit Options

Sl. No.ProgrammeSemester NoCourse Choice
1 IP 1 Core
2 IP 3 Not Allowed
3 IP 5 Not Allowed
4 MR 1 Not Allowed
5 MR 3 Not Allowed
6 MS 5 Elective
7 RS 1 Elective
8 RS 2 Elective