Details of LS4103 (Autumn 2019)

Level: 4 Type: Theory Credits: 4.0

Course CodeCourse NameInstructor(s)
LS4103 Developmental Biology Mohit Prasad,
Sreeramaiah Gangappa

Syllabus
BASIC CONCEPTS OF DEVELOPMENT

Definitions and Historical concepts of developmental biology, Potency, commitment, specification, induction, competence, determination and differentiation; morphogenetic gradients; cell fate and cell lineages; stem cells; genomic equivalence and the cytoplasmic determinants; Regulation of gene expression in development; Reaction diffusion and embryonic development; imprinting; mutants and transgenics in analysis of development.

GAMETOGENESIS

Fertilization and early development: Production of gametes, cell surface molecules in sperm-egg recognition in animal ; zygote formation, cleavage, blastula formation, embryonic fields, gastrulation and formation of germ layers in animals; embryogenesis

MORPHOGENESIS AND ORGANOGENESIS IN ANIMALS

Cell aggregation and differentiation in Dictyostelium; axes and pattern formation in Drosophila, amphibia and chick; organogenesis vulva formation in Caenorhabditis elegans; eye lens induction, limb development and regeneration in vertebrates; post embryonic development-larval formation, metamorphosis; environmental regulation of normal development; sex determination.

AGING AND SENESCENCE

References
1.Developmental Biology (8th Edition), S. F. Gilbert; Sinauer Associates, Sunderland, MA.

2.Principles of Development, Lewis Wolpert; Oxford University Press

Course Credit Options

Sl. No.ProgrammeSemester NoCourse Choice
1 IP 1 Not Allowed
2 IP 3 Core
3 IP 5 Not Allowed
4 MR 1 Not Allowed
5 MR 3 Not Allowed
6 MS 7 Core
7 RS 1 Elective
8 RS 2 Elective