Details of LS4103 (Autumn 2019)
| Level: 4 | Type: Theory | Credits: 4.0 |
| Course Code | Course Name | Instructor(s) |
|---|---|---|
| LS4103 | Developmental Biology | Mohit Prasad, Sreeramaiah N Gangappa |
| Syllabus |
|---|
| BASIC CONCEPTS OF DEVELOPMENT
Definitions and Historical concepts of developmental biology, Potency, commitment, specification, induction, competence, determination and differentiation; morphogenetic gradients; cell fate and cell lineages; stem cells; genomic equivalence and the cytoplasmic determinants; Regulation of gene expression in development; Reaction diffusion and embryonic development; imprinting; mutants and transgenics in analysis of development. GAMETOGENESIS Fertilization and early development: Production of gametes, cell surface molecules in sperm-egg recognition in animal ; zygote formation, cleavage, blastula formation, embryonic fields, gastrulation and formation of germ layers in animals; embryogenesis MORPHOGENESIS AND ORGANOGENESIS IN ANIMALS Cell aggregation and differentiation in Dictyostelium; axes and pattern formation in Drosophila, amphibia and chick; organogenesis vulva formation in Caenorhabditis elegans; eye lens induction, limb development and regeneration in vertebrates; post embryonic development-larval formation, metamorphosis; environmental regulation of normal development; sex determination. AGING AND SENESCENCE |
| References |
|---|
| 1.Developmental Biology (8th Edition), S. F. Gilbert; Sinauer Associates, Sunderland, MA.
2.Principles of Development, Lewis Wolpert; Oxford University Press |
Course Credit Options
| Sl. No. | Programme | Semester No | Course Choice |
|---|---|---|---|
| 1 | IP | 1 | Not Allowed |
| 2 | IP | 3 | Core |
| 3 | IP | 5 | Not Allowed |
| 4 | MR | 1 | Not Allowed |
| 5 | MR | 3 | Not Allowed |
| 6 | MS | 7 | Core |
| 7 | RS | 1 | Elective |
| 8 | RS | 2 | Elective |