Details of CH2202 (Spring 2020)
| Level: 2 | Type: Theory | Credits: 3.0 |
| Course Code | Course Name | Instructor(s) |
|---|---|---|
| CH2202 | Reaction Mechanisms in Organic Chemistry | Subhajit Bandyopadhyay, Suman De Sarkar |
| Syllabus |
|---|
| 1. Introduction: Importance of understanding reaction mechanisms, recap of the molecular
orbital pictures of the C-C bonds and the common functional groups. (3 Lectures) 2. Concept of stability: Resonance, hyperconjugation, inductive effects; Stability of reactive intermediates: carbocations (including non-classical carbocations), carbanions and radicals. (6 Lectures) 3. Strengths of acids/bases (2 Lectures) 4. Substitution Reactions: Nucleophilic reactions of aliphatic and aromatic compounds: SN1, SN2 (Walden inversion, basic stereochemistry), SNi, SNAr (6 Lectures) 5. Elimination reactions : E1, E2, E1cb, Zaytseff and Hoffmann; (4 Lectures) 6. Addition reactions: addition to C=C and aryl systems; nucleophilic addition to C=O, C=N, conjugated olefins and carbonyls; conjugate addition reactions; (6Lectures) 7. (C=O addition including ylides: sulphur and phosphorous ylides; Umpolung; basic organometallic reagents and their chemistry) coupling reactions eg. Suzuki, Heck, Nigishi, and metathesis reactions (4 Lectures) |
| References |
|---|
| References:
1. Peter Sykes, A Guidebook to Mechanism in Organic Chemistry 2. L. G. Wade, Jr. Organic Chemistry. 5th ed. 3. Jonathan Clayden, Nick Greeves, and Stuart Warren Organic Chemistry |
Course Credit Options
| Sl. No. | Programme | Semester No | Course Choice |
|---|---|---|---|
| 1 | IP | 2 | Not Allowed |
| 2 | IP | 4 | Not Allowed |
| 3 | IP | 6 | Not Allowed |
| 4 | MR | 2 | Not Allowed |
| 5 | MR | 4 | Not Allowed |
| 6 | MS | 4 | Core |
| 7 | RS | 1 | Not Allowed |
| 8 | RS | 2 | Not Allowed |