Details of CH2202 (Spring 2020)

Level: 2 Type: Theory Credits: 3.0

Course CodeCourse NameInstructor(s)
CH2202 Reaction Mechanisms in Organic Chemistry Subhajit Bandyopadhyay,
Suman De Sarkar

1. Introduction: Importance of understanding reaction mechanisms, recap of the molecular
orbital pictures of the C-C bonds and the common functional groups. (3 Lectures)
2. Concept of stability: Resonance, hyperconjugation, inductive effects; Stability of reactive
intermediates: carbocations (including non-classical carbocations), carbanions and
radicals. (6 Lectures)
3. Strengths of acids/bases (2 Lectures)
4. Substitution Reactions: Nucleophilic reactions of aliphatic and aromatic compounds:
SN1, SN2 (Walden inversion, basic stereochemistry), SNi, SNAr (6 Lectures)
5. Elimination reactions : E1, E2, E1cb, Zaytseff and Hoffmann; (4 Lectures)
6. Addition reactions: addition to C=C and aryl systems; nucleophilic addition to C=O,
C=N, conjugated olefins and carbonyls; conjugate addition reactions; (6Lectures)
7. (C=O addition including ylides: sulphur and phosphorous ylides; Umpolung; basic
organometallic reagents and their chemistry) coupling reactions eg. Suzuki, Heck,
Nigishi, and metathesis reactions (4 Lectures)

1. Peter Sykes, A Guidebook to Mechanism in Organic Chemistry
2. L. G. Wade, Jr. Organic Chemistry. 5th ed.
3. Jonathan Clayden, Nick Greeves, and Stuart Warren Organic Chemistry

Course Credit Options

Sl. No.ProgrammeSemester NoCourse Choice
1 IP 2 Not Allowed
2 IP 4 Not Allowed
3 IP 6 Not Allowed
4 MR 2 Not Allowed
5 MR 4 Not Allowed
6 MS 4 Core
7 RS 1 Not Allowed
8 RS 2 Not Allowed