Details of CH4202 (Spring 2020)

Level: 4 Type: Theory Credits: 4.0

Course CodeCourse NameInstructor(s)
CH4202 Natural Products and Medicinal Chemistry Alakesh Bisai,
Dibyendu Das

Carbohydrates: Carbohydrate nomenclature, structures, anomeric effect: principles and applications, mutarotation, functional group modifications, glycosylations, biological importance of carbohydrates, enzymatic glycosylations, vaccine design. Proteins and Amino Acids: alpha-Amino Acids, other amino acids and their importance, isoelectric point, preparation of amino acids, reactions of AA, peptide bond formation, reagents-reactions, solid phase peptide synthesis, peptides and proteins. Lipids, terpenoids, prostaglandins, steroids, polyketides: Fatty Acids: Saturated, unsaturated (nomenclature), roles in biological processes, detergents, Fats & Oils, Phospholipids, cellular membrane. Prostaglandins; Terpenes; Steroids; Polyketides: Synthesis and Biosynthetic Mechanisms; Alkaloids: Classification, Indole alkaloids (the largest class of the alkaloids) Synthesis of some alkaloids: Mannich, Pictet-Spengler, and Bischler-Napieralski reactions; Dyes: Roles in plants and animals. Classifications: Indigoid, anthraquinonoid, flavonoids, dihydropyranoids, carotenoids, etc.
Introduction to Medicinal Chemistry
Biopharmaceutical Properties of Drug Substances
Pharmacologic Activity
Drug Design
Drug/Receptor Interactions
Drug Resistance and Metabolism
Metal-Based Drugs


Course Credit Options

Sl. No.ProgrammeSemester NoCourse Choice
1 IP 2 Not Allowed
2 IP 4 Core
3 IP 6 Not Allowed
4 MR 2 Not Allowed
5 MR 4 Not Allowed
6 MS 8 Core
7 RS 1 Elective
8 RS 2 Elective