Details of CH4202 (Spring 2020)
| Level: 4 | Type: Theory | Credits: 4.0 |
| Course Code | Course Name | Instructor(s) |
|---|---|---|
| CH4202 | Natural Products and Medicinal Chemistry | Alakesh Bisai, Dibyendu Das |
| Syllabus |
|---|
| Carbohydrates: Carbohydrate nomenclature, structures, anomeric effect: principles and applications, mutarotation, functional group modifications, glycosylations, biological importance of carbohydrates, enzymatic glycosylations, vaccine design. Proteins and Amino Acids: alpha-Amino Acids, other amino acids and their importance, isoelectric point, preparation of amino acids, reactions of AA, peptide bond formation, reagents-reactions, solid phase peptide synthesis, peptides and proteins. Lipids, terpenoids, prostaglandins, steroids, polyketides: Fatty Acids: Saturated, unsaturated (nomenclature), roles in biological processes, detergents, Fats & Oils, Phospholipids, cellular membrane. Prostaglandins; Terpenes; Steroids; Polyketides: Synthesis and Biosynthetic Mechanisms; Alkaloids: Classification, Indole alkaloids (the largest class of the alkaloids) Synthesis of some alkaloids: Mannich, Pictet-Spengler, and Bischler-Napieralski reactions; Dyes: Roles in plants and animals. Classifications: Indigoid, anthraquinonoid, flavonoids, dihydropyranoids, carotenoids, etc.
Introduction to Medicinal Chemistry Biopharmaceutical Properties of Drug Substances Pharmacologic Activity Drug Design Drug/Receptor Interactions Drug Resistance and Metabolism Metal-Based Drugs |
| References |
|---|
Course Credit Options
| Sl. No. | Programme | Semester No | Course Choice |
|---|---|---|---|
| 1 | IP | 2 | Not Allowed |
| 2 | IP | 4 | Core |
| 3 | IP | 6 | Not Allowed |
| 4 | MR | 2 | Not Allowed |
| 5 | MR | 4 | Not Allowed |
| 6 | MS | 8 | Core |
| 7 | RS | 1 | Elective |
| 8 | RS | 2 | Elective |