Details of CH5103 (Autumn 2022)
| Level: 5 | Type: Theory | Credits: 4.0 |
| Course Code | Course Name | Instructor(s) |
|---|---|---|
| CH5103 | Supramolecular Chemistry and Applications | Chilla Malla Reddy, Debasish Haldar |
| Syllabus |
|---|
| Course content
Basic concept and principles; History, Molecular recognition, Hydrogen Bonds: Definition, Structure and Stability, strength, Secondary Electrostatic Interactions in Hydrogen Bonding Arrays Non-covalent interactions: Ion pairing, Ion-Dipole Interactions, Dipole-Dipole interactions, Dipole-Induced Dipole and Ion-Induced Dipole interactions, van der Waals or Dispersion Interactions, Hydrogen bonding, Halogen bonding, Cation-= interactions, Anion-= interactions, =-= interactions, Closed shell interactions, Aromatic-Aromatic Interactions: Benzene Crystals, Edge-to-face vs. =-= Stacking Interactions, N-H---= interactions, Sulfur-aromatic interactions, Benzene-Hexafluorobenzene =-stacking. Biological supramolecular systems: Ionophores, Porphyrin and other Tetrapyrrolic Macrocycles, Coenzymes, Neurotransmitters, DNA and Biochemical Self-assembly. Supramolecular reactivity Biomimetic systems and Artificial receptors: (a) Cation Binding Hosts - Podand, Crown Ether, Cryptand, Spherand; Nomenclature, Selectivity and Solution Behaviour; Alkalides, Electrides, Calixarenes and Siderophores. (b) Anion binding hosts - Challenges and Concepts, Biological Receptors, Conversion of Cation Hosts to Anion Hosts, Neutral Receptors, Metal-Containing Receptors, Cholapods. (c ) Ion Pair Receptors - Contact Ion Pairs, Cascade Complexes, Remote Anion and Cation Binding Sites, Symport and Metals Extraction. (d) Hosts for Neutral Receptors -Clathrates, Inclusion Compounds, Zeolites, Intercalates, Coordination Polymers, Guest Binding by Cavitands and Cyclodextrins, cucurbituril. Transport processes; Dynamic Combinatorial chemistry Supramolecular chirality and chirality imprinting Solid-State Chemistry Organic Crystal Structures, Metal Organic Frameworks (MOFs), Covalent Organic Frameworks, Polymorphism, Solvates, Co-Crystals, Salts, Amarphous Materials Crystal Engineering: Supramolecular Synthons, Structure-Property Correlation, Design of Solids, Design of Properties, phase transformations, stimuli responsive solids Topochemical 2+2 cycloadditions in cinnamic acids under light Topochemical photopolymerization in crystals |
| References |
|---|
| 1. Supramolecular Chemistry by J. W. Steed & J. L. Atwood, 2ndEdn John Wiley, 2009.
2. Crystal Engineering. The Design of Organic Solids by G.R. Desiraju, Elsevier, 1989. 3. J. M. Lehn, Supramolecular Chemistry, VCH, Weinheim, 1995 |
Course Credit Options
| Sl. No. | Programme | Semester No | Course Choice |
|---|---|---|---|
| 1 | IP | 1 | Elective |
| 2 | IP | 3 | Elective |
| 3 | IP | 5 | Not Allowed |
| 4 | MR | 1 | Elective |
| 5 | MR | 3 | Elective |
| 6 | MS | 3 | Not Allowed |
| 7 | MS | 5 | Not Allowed |
| 8 | MS | 7 | Not Allowed |
| 9 | MS | 9 | Elective |
| 10 | RS | 1 | Elective |
| 11 | RS | 2 | Elective |