Details of CH4203 (Spring 2023)

Level: 4 Type: Laboratory Credits: 4.0

Course CodeCourse NameInstructor(s)
CH4203 Organic Chemistry Laboratory Alakesh Bisai,
Biplab Maji

Preamble
This laboratory course will focus on the synthesis and characterization of small organic molecules based on the advanced methodologies discovered in the last 1-2 decade/s or so.
Students will learn the spectroscopic techniques to characterize the products obtained from these syntheses. At the end of this laboratory, students will be benefitted for doing their 5 th year BS-MS research in the Dept. of Chemical Sciences.

Syllabus
Organometallic Chemistry
Mizoriki-Heck-Coupling for the Synthesis of Cinnamates
Synthesis of Disubstituted Alkynes using Sonogashira Coupling
Synthesis of Biaryls using Suzuki Coupling Reactions
Azide-Alkyne Click Reactions: Synthesis of Substituted Triazoles

Carbon-Carbon Bond-Forming Methodologies
Ugi Multicomponent Coupling for a-Amino Acid Derivatives
Synthesis b-Aminocarbonyls via Mannich Reaction
Synthesis a-Hydroxycarbonyls via Benzoin Condensation
Stetter Reaction for the Synthesis Multisubstituted Carbonyls

Asymmetric Synthesis
Asymmetric Reduction of Carbonyls using CBS-Catalyst
Synthesis of L-Prolinamide Catalysts
Asymmetric Aldol Reactions
Synthesis of Organocatalyst for Aldol Reaction
Asymmetric Michael Addition onto b-Nitrostyrenes Catalyzed by L-Prolinamide

References

Course Credit Options

Sl. No.ProgrammeSemester NoCourse Choice
1 IP 2 Not Allowed
2 IP 4 Elective
3 IP 6 Not Allowed
4 MP 2 Not Allowed
5 MP 4 Not Allowed
6 MR 2 Not Allowed
7 MR 4 Not Allowed
8 MS 10 Not Allowed
9 MS 4 Not Allowed
10 MS 6 Not Allowed
11 MS 8 Core
12 RS 1 Elective
13 RS 2 Elective