Details of CH3102 (Autumn 2025)
| Level: 3 | Type: Theory | Credits: 4.0 |
| Course Code | Course Name | Instructor(s) |
|---|---|---|
| CH3102 | Organic Chemistry I | Rahul Banerjee, Supratim Banerjee |
| Syllabus |
|---|
|
1. Reactions involving Nucleophilic Carbon Intermediates (12 Lectures) (a) Aldol reaction, (b) Mannich reaction, (c) Crossed aldol, (d) Aldol condensation, (e) Nitro aldol; (f) Strecker reaction (g) Cannizaro reactions: Intermolecular & intramolecular version (concept of hydride delivery from organic molecules) (h) Perkin reaction, (i) Knoevenagel condensation, (j) Claisen reaction (k) Dickmann condensation 2. Rearrangement Reactions (10 Lectures) Electrophilic Rearrangements: (a) Wagner-Meerwein, (b) Pinacol-pinacolone, (c) Demzanov reaction (d) Dienone-phenol rearrangement (e) Beckmann rearrangement, (f) Hofmann degradation, (g) Lossen rearrangement, (h) Curtius rearrangement, (i) Wolff rearrangement, (j) Schmidt reaction, (k) Baeyer-Villiger oxidation; Nucleophilic Rearrangements:(a) Benzil-Benzilic acid rearrangement (b) Favorski rearrangement 3. Oxidations (10 Lectures) (a) Ozonolysis (b) OsO 4 and KMnO 4 oxidation of olefins (dihydroxylation) (c) SeO 2 -oxidation of olefins; Oxidations using Cr(VI)-complexes: (a) Jones oxidation (b) PDC oxidation (c) PCC oxidation (c) Dauben oxidation; Activated DMSO/DMS Complexes (a) Swern Oxidation (b) Corey-Kim oxidation; Hypervalent iodine reagents: (a) IBX Oxidation (b) Dess-Martin Periodinane (DMP) (c) PIDA oxidation 4. Reductions (8 Lectures) Reduction of carbonyls using metal hydrides (a) NaBH 4 (b) NaBH 3 CN (c) LiBH 4 (d) LiAlH 4 (e) BH 3 or B 2 H 6 (f) DiBAL-H (g) L-selectride; Ketone reduction under (a) Clemension reduction, (b) Wolf- Kishner reduction (c) Mozingo reduction; Catalytic hydrogenation and imide reductions of C-C double and triple bonds; Reduction using dissolving metals: (a) Birch reduction, (b) Acyloin condensation, (c) Bouveault-Blanc reduction; Reductions under transfer hydrogenation; Meerwein- Ponndorf-Verley (MPV) reduction & Oppenuer oxidation |
| References |
|---|
| References
1. Guidebook to Mechanism in Organic Chemistry, by Peter Sykes, 6$^th $ Edition. 2. Advanced Organic Chemistry: Reactions, Mechanisms, and Structure, by Jerry March, 5$^th $ Edition. 3. Organic Chemistry, by J. Clayden, N. Greeves, S. Warren and P. Wothers. 4. Organic Chemistry, by I. L. Finar, Longmans, vol. 1 & 2, 4$^th Edition |
Course Credit Options
| Sl. No. | Programme | Semester No | Course Choice |
|---|---|---|---|
| 1 | IP | 1 | Not Allowed |
| 2 | IP | 3 | Not Allowed |
| 3 | MP | 1 | Not Allowed |
| 4 | MP | 3 | Not Allowed |
| 5 | MR | 1 | Elective |
| 6 | MR | 3 | Not Allowed |
| 7 | MS | 3 | Not Allowed |
| 8 | MS ( Chemical Sciences ) | 5 | Core |
| 9 | MS | 7 | Not Allowed |
| 10 | MS | 9 | Not Allowed |
| 11 | RS | 1 | Not Allowed |
| 12 | RS | 2 | Not Allowed |