Details of CH5102 (Autumn 2025)
| Level: 5 | Type: Theory | Credits: 4.0 |
| Course Code | Course Name | Instructor(s) |
|---|---|---|
| CH5102 | Glycochemistry, glycobiology and Medicinal Chemistry | Balaram Mukhopadhyay |
| Syllabus |
|---|
| Medicinal Chemistry
1.Biopharmaceutical Properties of Drug Substances 2.Pharmacologic Activity 3.Drug Design 4.Drug/Receptor Interactions 5.Drug Resistance and Metabolism 6.Pharmacodynamics and pharmacokinetics 7.Drug Targets: Enzymes, Receptors, Nucleic Acids. 8.Case Studies of Important Drugs Glycochemistry and Glycobiology 1.Introduction to carbohydrates 2.Classification of carbohydrates 3.ABO system and blood group antigens 4.Introduction to Synthetic Carbohydrate Chemistry: Mutarotation, Anomeric Effect, Glycosylation, Protecting group manipulations 5.Synthesis of Oligosaccharides: Retrosynthesis, orthogonal protecting group manipulations, stereoselective glycosylation, global deprotection, few reaction mechanisms 6.Challenges of 1,2-cis mannoside and rhamnoside formation, systematic development of strategies in this area 7.Carbohydrate-protein interaction, glycol-cluster effect, multivalency in carbohydrates, dendrimers, nanoparticles 8.Synthetic vaccine design and future scope |
| References |
|---|
Course Credit Options
| Sl. No. | Programme | Semester No | Course Choice |
|---|---|---|---|
| 1 | IP | 1 | Not Allowed |
| 2 | IP | 3 | Not Allowed |
| 3 | IP | 5 | Not Allowed |
| 4 | MP | 1 | Not Allowed |
| 5 | MP | 3 | Elective |
| 6 | MR | 1 | Elective |
| 7 | MR | 3 | Elective |
| 8 | MS | 3 | Not Allowed |
| 9 | MS | 5 | Not Allowed |
| 10 | MS | 7 | Not Allowed |
| 11 | MS | 9 | Elective |
| 12 | RS | 1 | Elective |
| 13 | RS | 2 | Elective |