Details of CH2204 (Spring 2025)
| Level: 2 | Type: Theory | Credits: 2.0 |
| Course Code | Course Name | Instructor(s) |
|---|---|---|
| CH2204 | Organic Chemistry II | Biplab Maji, Suman De Sarkar |
| Syllabus |
|---|
| Syllabus:
1. Reactions of Alkenes (4 Lectures) Hydration, addition HX, halogenation, epoxidation, cyclopropanation, hydroboration, hydroxylation, ozonolysis, hydrometallation, hydrogenation, and polymerization reactions. 2. Reactions of Carbonyl Compounds (8 Lectures) Addition of O-, N-, C-nucleophiles to carbonyl compounds and imines. 1,2- and 1,4- additions. Addition-elimination mechanism: Reactions of carboxylic acid derivatives. Umpolung reactions. 3. Aromatic Compounds and their Reactions (4 Lectures) Monocyclic aromatic hydrocarbon, electrophilic aromatic Substitution and nucleophilic aromatic substitution reactions, substituent effects, benzynes, basic reactions of heteroaromatic compounds. 4. Stereochemistry, Conformation and Reactivity (8 Lectures) Representation of molecules in Fischer, Saw horse, flying-wedge and Newman formulae and their inter translations, symmetry elements, molecular chirality Stereocentres: stereogenicity, chirotopicity, systems involving 1,2,3 centers D/L and R/S descriptor, threo/erythro and syn/anti nomenclatures cis/trans, syn/anti, E/Z descriptors (for C=C, C=N). Conformation: Conformational nomenclature, eclipsed, staggered, gauche and anti; dihedral angle, torsion angle, energy barrier of rotation, relative stability of conformers on the basis of steric effect, dipole-dipole interaction, H-bonding etc. Specific rotation, optical purity (enantiomeric excess) Stereochemistry and conformation of cyclic compounds Dynamic stereochemistry: Conformation and reactivity |
| References |
|---|
| Suggested readings:
1. Peter Sykes; A Guidebook to Mechanism in Organic Chemistry. 2. Jonathan Clayden, Nick Greeves, and Stuart Warren; Organic Chemistry. 3. Michael B. Smith, Jerry March; March's Advanced Organic Chemistry: Reactions, Mechanisms, and Structure. 4. Stereochemistry of Organic Compounds: Principles and Applications by D. Nasipuri. 5. Stereochemistry of Carbon Compounds by E. L. Eliel and S. H. Wilen. |
Course Credit Options
| Sl. No. | Programme | Semester No | Course Choice |
|---|---|---|---|
| 1 | IP | 2 | Not Allowed |
| 2 | IP | 4 | Not Allowed |
| 3 | IP | 6 | Not Allowed |
| 4 | MP | 2 | Not Allowed |
| 5 | MP | 4 | Not Allowed |
| 6 | MR | 2 | Not Allowed |
| 7 | MR | 4 | Not Allowed |
| 8 | MS | 10 | Not Allowed |
| 9 | MS | 4 | Core |
| 10 | MS | 6 | Not Allowed |
| 11 | MS | 8 | Not Allowed |
| 12 | RS | 1 | Not Allowed |
| 13 | RS | 2 | Not Allowed |