INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH KOLKATA

... towards excellence in science

An Autonomous Institution, Under the Ministry of Education, Government of India

Rituparna Sinha Roy

Associate Professor
Dept: Biological Sciences (DBS), Chemical Sciences (DCS)
E-mail: rituparna [at] iiserkol.ac.in
Personal homepage: Click Here

Research Interest:
 

Research Area: Peptide based therapeutics, Nanomedicine, drug delivery, biomimetic chemistry , chemical biology, supramolecular chemistry, applied biomaterials and cancer biologyRituparna Sinha Roy is interested in using biomimetic design strategies to develope novel molecules and therapeutic approach for biology and medicine. She is integrating protein engineering and nanotechnology for therapeutic purpose, with a special interest in cancer. Her research lies at the interface of chemistry, protein engineering , nanotechnology and medicine. She is developing platform technologies and tools for stabilizing and probing protein structure and function. Her research will focus on engineering stabilized biomolecules for therapy in the context of siRNA delivery, vaccine development and regenerative medicine.

Academic Background:

  1. PhD (Conformational analysis of designed alpha omega hybrid peptides), Molecular Biophysics Unit,IISc (Indian Institute of Science (IISc Bangalore)), 2005
  2. MSc (Physical Chemistry) (Physical Chemistry), Jadavpur University, 1999
  3. BSc(Chemistry Hons) (Chemistry), Jadavpur University, 1997

Positions:

  1. Associate Professor, IISER Kolkata (current)
  2. Assistant Professor, Indian Institute of Science Education and Research Kolkata (2011 - 2018)
  3. Postdoc, Department of Medicine, Harvard Medical School (2007 - 2011)
  4. Postdoc, The Scripps Research Institute, San Diego (2005 - 2007)

Awards and Honors:

  1. SERB-POWER fellowship from DST-SERB (2021)
  2. OPPI Woman Scientist Award 2020 from Organisation of Pharmaceutical Producers of India (OPPI) (2020)
  3. Editorial Advisory Board Member of ACS Applied Bio Materials from ACS Applied Biomaterials (2019)
  4. Executive Council Member Indian Chemical Biology from Indian Chemical Biology (2018)
  5. Ramalingaswamy from DBT (2011)
  6. Travel Award from American Society for Pharmacology and Experimental Therapeutics, USA (2010)
  7. Postdoctoral Scientist Award from American Society for Pharmacology and Experimental Therapeutics, USA (2009)
  8. Best PhD Thesis Award (Shamrao Kaikini Medal) in the area of Biological Sciences and Chemical Scien from Indian Institute of Science, Bangalore (2006)

Selected Publications:

  1. Mallick, Argha Mario; Biswas, Abhijit; Mishra, Sukumar; Jadhav, Sonali; Chakraborty, Kasturee; Tripathi, Archana; Mukherjee, Arnab and Sinha Roy, Rituparna. 2023."Engineered vitamin E-tethered non-immunogenic facial lipopeptide for developing improved siRNA based combination therapy against metastatic breast cancer ." Chemical Science (selected for outside front page of the journal; Highlighted by Nature India), 14, 7842
  2. Chakraborty, Kasturee; Biswas, Abhijit; Mishra, Sukumar; Mallick, Argha Mario; Tripathi, Archana; Jan, Somnath and SinhaRoy, Rituparna. 2023."Harnessing Peptide-Functionalized Multivalent Gold Nanorods for Promoting Enhanced Gene Silencing and Managing Breast Cancer Metastasis." ACS Applied Bio Materials (selected as journal cover page), 6, 458-472
  3. Mallick, Argha Mario; Tripathi, Archana; Mishra, Sukumar; Mukherjee, Asmita; Dutta, Chiranjit; Chatterjee, Ananya and Sinha Roy, Rituparna. 2022."Emerging approaches for enabling RNAi Therapeutics ." Chemistry-An Asian Journal (selected as hot topic: drug delivery; selected as hot topic RNA) , e202200451, 1
  4. Chakraborty, Kasturee; Tripathi, Archana; Mishra, Sukumar; Mallick, Argha Mario and Sinha Roy, Rituparna. 2022."Emerging concepts in designing multifunctional nanomedicine for cancer treatment. ." Bioscience Reports, 42, 1
  5. Ghosh, Snehasish; Gayen, Paramita; Jan, Somnath; Kishore, Anyam Vijay; Kumar, Vinod; Mallick, Argha Mario; Mukherjee, Asmita; Nandi, Samit Kumar and SinhaRoy, Rituparna. 2020."Bio-inspired Non-immunogenic Multifunctional Sealant for Efficient Blood Clotting and Suture Free Wound Closure ." Biomaterials Science and Engineering (selected as journal cover page; highlighted by Nature India), 6, 6378-6393

All Publications: Click Here