Supervisor

Arnab Gupta

Principal Investigator

Arnab completed his PhD in 2006-07 from CSIR-Indian Institute of Chemical Biology in the field of human genetics under the supervision of Prof. Kunal Ray. Subsequently, he moved to US for his postdoctoral training with Profs. Svetlana Lutsenko and Ann Hubbard at The Johns Hopkins University. His field of study was to elucidate the regulations of the human copper pumps and channels. After a brief stint at the University of Calcutta as a Ramanujan Fellow, he set up his independent research group at IISER Kolkata. Presently at IISER Kolkata, using various cutting edge techniques especially high-resolution imaging and molecular dynamic studies, his group is probing the secretory pathway that the copper ATPase ATP7A and ATP7B traverses to export copper from the cell. The second line of the group's interest is to understand the copper mediated endocytic regulation of the primary copper importer CTR1. The research of the group is funded through multiple funding agencies, i.e., The Wellcome Trust DBT India Alliance, DST-Core research grant, DST-Special Call, ICMR- Adhoc Project Program, MHRD-STARS and Intramural funding from IISER Kolkata.

Current Lab Members

Member 1

Salauddin Sekh

Lab Manager

I oversee all the macro as well as micro management in Arnab's Lab. In my leisure time, I help others in their experiments.

Member 1

Sharon Mary Jose

Senior Research Fellow

I am trying to understand the the trafficking regulation of the homologous Cu-ATPases ATP7A and ATP7B. Specifically, I want to understand the role of the structural domains of these transporters in determining trafficking polarity.

Member 1

Raviranjan Pandey

Senior Research Fellow

I am interested in exploring therapeutics aspects of anti-oxidants for Wilson's disease. I am also exploring pathways of copper toxicity.

Member 1

Aayatti Mallick Gupta

Postdoctoral Fellow

Structural and functional studies on the role of the copper ATPases in heavy metal detoxification.

Member 1

Kaustav Chakraborty

Postdoctoral Fellow

Cellular copper homeostasis and it's interplay in physiology and pathology in C elegans.

Member 1

Krishanu Dutta

Senior Research Fellow

I am trying to generate animal models for Menkes and Wilsons disease.

Member 1

Mainak Chakraborty

Senior Research Fellow

I am studying the role of post-translational modification and regulation of Cu-ATPases.

Member 1

Swastika Dey

Junior Research Fellow

I am investigating the alterations in cupro-proteome during leishmania infection and it's implications in host-pathogen interaction.

Member 1

Brindaban Maji

Junior Research Fellow

The effects of heavy metal toxicity in mammalian liver. I am also trying to decifer the role of copper in regulation of cholesterol homeostasis.

Member 1

Bratati Dutta

Junior Research Fellow

I am exploring the role of copper transporters during adipogenesis.

Member 1

Sharanya Bhattacharya

Integrated PhD

I am exploring ideas.

Member 1

Mrittika Paul

Junior Research Fellow

I just joined Arnab's lab. I am exploring ideas.

Member 1

Debosmita Bhattacharya

Junior Research Fellow

I just joined Arnab's lab. I am exploring ideas.

Member 1

Arpan Narayan Roy

BS-MS 5th Year

I am developing and characterizing small molecules for therapy of Wilson disease, in collaboration with Prof. Amitava Das, Chemistry, IISER Kolkata.

Member 1

Tisha Dash

BS-MS 5th Year

I am using MD simulation to study the structure-function of CTR1.

Member 1

Borkar Aditya Ashok

BS-MS 5th Year

I am exploring ideas.

Member 1

Avijit Majumder

BS-MS 5th Year

Possible role of copper in endosomal cholesterol trafficking in hepatocytes.

Member 1

Baivab Kumar Saha

BS-MS 5th Year

Stochastic model of copper induced ATP7B trafficking in polarized epithelia.

Lab Alumni

Member 1

Santanu Das

Post Doctoral fellow at Children's Hospital of Philadelphia

Member 1

Sumanta Kar

Post Doctoral fellow at Leibniz-Forschungsinstitut für Molekulare Pharmakologie, Berlin (FMP-Berlin)

Member 1

Ruturaj

Post Doctoral fellow at Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG)

Member 1

Saptarshi Maji

Post Doctoral fellow at Institute of Molecular and Cellular Pharmacology IPMC-CNRS

Member 1

Rupam Paul

Post Doctoral fellow at University of Florida

Member 1

Asmita Pal

Post Doctoral fellow at University of Nebraska Medical Center

Member 1

Siddhanta V. Nikte

Post Doctoral fellow at Goethe University Frankfurt

Member 1

Shuvendu Kr Chatterjee

...

Member 1

Sohini Dutt

Grad student at University of Maryland

Member 1

Saptarshi Maji

Research Scholar at Indian Institue of Science Education and Research Kolkata

Member 1

Rounak Dutta

Grad student at Stony Brook University

Member 1

Fathima Zahrana

..

Member 1

Archita Ghosh

Assistant Manager at Bangiya Gramin Vikash Bank

Member 1

Soumyendu Saha

Grad Student at McGill University

Member 1

Prodyuti

..

Member 1

Indira Bhattacharya

Grad Student at University of Maryland

Member 1

Pruthwiraj

Entrepreneur

Member 1

Samarpita Sen

Grad student at University of Cambridge

Member 1

Taniya Mandal

Grad Student at Francis Crick Institute

Member 1

Ankita Nayak

Grad Student at National University of Singapore

Member 1

Ameena Mohammed

Grad student at University of Tubingen

Member 1

Adrija Chakrabarty

Graduate Student at CeMM Center for Molecular Medicine Vienna

Member 1

Monalisa Mishra

Graduate Student at Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG)

Interns

Sakir Gazi

Indian Association Cultivation Science

(Summer'24)

Preyarshri

University of Calcutta

(Summer'24)

Poulomi Patra

University of Kalyani

(Summer'24)

Oindrilla Acharya

Jadavpur University

(Spring'23)

Tithi Dutta

University of Kalyani

(Spring'23)

Subhanjan Bhattacharya

MAKAUT

(Spring'23)

Tanima Biswas

Indian Association Cultivation Science

(Summer'23)

Sarmistha Paul

Indian Association Cultivation Science

(Summer'23)