Amit Kumar Mandal

Dept: Biological Sciences (DBS)
E-mail: amitkm [at]
Personal homepage: Click Here

Research Interest:

Molecular Medicine - Structural Biology of proteins that are important in human diseases, Clinical Proteomics of biological fluids and tissues from patient sample, Imaging of clinically important molecules in human tissues

Academic Background:

  1. PhD (Biophysical Chemistry), Bose Institute (Jadavpur University), 2004
  2. MSc (Physical Chemistry), Presidency College (University of Calcutta), 1992


  1. Faculty, IISER Kolkata (current)
  2. Professor, St. John's Research Institute, St. John's National Academy of Health Sciences, Bangalore (2011 - 2019)
  3. Associate Professor, St. John's Research Institute, St. John's National Academy of Health Sciences, Bangalore (2007 - 2011)
  4. Postdoctoral Fellow, Indian Institute of Science, Bangalore (2005 - 2006)
  5. Postdoctoral Fellow, University of Texas Health Science Center, San Antonio, Texas, USA (2002 - 2003)

Awards and Honors:

  1. Centers of Innovation (COI) [] from WATERS, USA (2013)

Selected Publications:

  1. 46. Muralidharan, Monita; Bhat, Vijay and Mandal, Amit Kumar. 2019."Structural analysis of glycated hemoglobin using native mass spectrometry." FEBS J, 287, 1247-1254
  2. 37. Das, Rajdeep; Mitra, Amrita; Mitra, Gopa; Maity, Dibyajyoti; Bhat, Vijay; Pal, Debnath; Ross, Cecil; Kurpad, Anura V and Mandal, Amit Kumar. 2018."Molecular insights of inhibition in sickle hemoglobin polymerization upon glutathionylation: hydrogen/deuterium exchange mass spectrometry and molecular dynamics simulation-based approach." Biochemical Journal, 475, 2153
  3. 24. Narayanan, Sreekala; Mitra, Gopa; Muralidharan, Monita; Mathew, Boby and Mandal, Amit Kumar. 2015."Protein Structure Function Correlation in Living Human Red Blood Cells Probed by Isotope Exchange-based Mass Spectrometry." Analytical Chemistry, 87, 11812
  4. 22. Srinivasu, Bindu Y; Mitra, Gopa; Muralidharan, Monita; Srivastava, Deepsikha; Pinto, Jennifer; Thankachan, Prashanth; Suresh, Sudha; Shet, Arun; Rao, Suguna; Ravikumar, Gayatri; Thomas, Tinku S; Kurpad, Anura V and Mandal, Amit Kumar. 2015."Beneficiary effect of nanosizing ferric pyrophosphate as food fortificant in iron deficiency anemia: evaluation of bioavailability, toxicity and plasma biomarker." Royal Society of Chemistry Advances, 5, 61678
  5. 19. Das, Rajdeep; Mitra, Gopa; Mathew, Boby; Ross, Cecil; Bhat, Vijay and Mandal, Amit Kumar. 2013."Automated Analysis of Hemoglobin Variants Using NanoLC-MS and Customized Databases." Journal of Proteome Research, 12, 3215

All Publications: Click Here