Bidisha Sinha
Associate Professor
Dept: Biological Sciences (DBS)
E-mail: bidisha.sinha [at] iiserkol.ac.in
Personal homepage: Click Here
Research Interest:
The theme of the lab is to understand how cells achieve a homeostatic mechanical state of their membrane during various processes/perturbations. We study how effective membrane tension is interlinked with endocytosis, receptor clustering, cell-cell fusion, migration, and cellular mechanoprotection.
Academic Background:
- PhD (Life Sciences), National Centre for Biological Sciences, 2007
Positions:
- Associate Professor, IISER Kolkata (current)
- Postdoctoral Fellow, Institut Curie (2007 - 2011)
Awards and Honors:
- Intermediate Fellowship from Wellcome Trust DBT India Alliance (2013)
- Ramanujan Fellowship from Department of Science and Technology, Govt. of India (2012)
Selected Publications:
- Chakraborty, Madhura; Sivan, Athul; Biswas, Arikta and Sinha, Bidisha. 2022."Early tension regulation coupled to surface myomerger is necessary for the primary fusion of C2C12 myoblasts.." Front. Physiol., 13, 976715
- Chakraborty, Madhura; Mukherjee, Baishali; Nalinakshan, Nanditha; Biswas, Arikta; Nayak, Rajesh Kumble and Sinha, Bidisha. 2022."Effect of heterogeneous substrate adhesivity of follower cells on speed and tension profile of leader cells in primary keratocyte collective cell migration.." Biology Open, 11, 058893
- Kumar, Rinku; Saha, Sajjita and Sinha, Bidisha. 2019."Cell spread area and traction forces determine myosin-II-based cortex thickness regulation." BBA Molecular Cell Research, 1866, 118516
- Biswas, Arikta; Kashyap, Purba; Datta, Sanchari; Sengupta, Titas and Sinha, Bidisha. 2019."Cholesterol Depletion by MbCD Enhances Cell Membrane Tension and Its Variations-Reducing Integrity." Biophysical Journal, 116, 1456-1468
- Biswas, Arikta; Alex, Amal and Sinha, Bidisha. 2017."Mapping cell membrane fluctuations reveals their active regulation and transient heterogeneities.." Biophysical Journal, 113, 1768-1781
All Publications: Click Here