... towards excellence in science

An Autonomous Institution, Under the Ministry of Education, Government of India

Partha Pratim Datta

Associate Professor
Dept: Biological Sciences (DBS)
E-mail: partha_datta [at]
Personal homepage: Click Here

Research Interest:

We are trying to understand the action mechanisms of an essential bacterial GTPase protein CgtA (Obg) that is a new drug target against increasing antimicrobial resistance. For this we use various Molecular Biological, Microbiological, Structural Biological and Computational tools. We are also interested in structure function study of certain plant viruses that cause huge economic loss in India and in the world.

Academic Background:

  1. PhD (Molecular Biology), IICB (Jadavpur University), 2002
  2. MSc (Biotechnology) (Biotechnology, Molecular Biology, Plant Molecular Biology, Microbiology), MKU, 1995
  3. BSc(Ag) Hons (Biochemistry, Genetics, Agril. Chemistry), BCKV, 1993


  1. Associate Professor, IISER Kolkata (current)
  2. Assistant Professor, IISER Kolkata (2009 - 2018)
  3. Research Scientist I, Wadsworth Center, NY State Dept. of Health, Albany, NY, USA (2008 - 2009)
  4. Research Affiliate, Wadsworth Center, Albany, NY, USA (2001 - 2008)

Awards and Honors:

  1. Robert J. Colinas Award for Outstanding Postdoctoral Research, from Wadsworth Center, Albany, USA (2007)
  2. Young Scientist Award from MEEGID (2000)

Selected Publications:

  1. Das, Sagarika; Chatterjee, Ananya and Datta, Partha Pratim. 2023."Knockdown experiment reveals an essential GTPase CgtA’s involvement on growth, viability, motility, morphology, and persister phenotypes in Vibrio cholerae." Microbiology Spectrum, 11(2), 1-23
  2. Das, Sagarika and Datta, Partha Pratim. 2022."Effect of a single amino acid substitution G98D in a ribosome-associated essential GTPase, CgtA, on the growth and morphology of Vibrio cholerae." Archives of Microbiology, 204, 1-12
  3. Jana, Soma and Datta, Partha Pratim. 2021."In silico analysis of bacterial translation factors reveal distinct translation event specific pI values." BMC Genomics, 22 (1), 220
  4. Koripella, Ravi Kiran; Sharma, Manjuli R.; Bhargava, Kalpana; Datta, Partha Pratim; Kaushal, Prem S.; Keshavan, Pooja; Spremulli, Linda L.; Banavali, Nilesh K. and Agrawal, Rajendra K.. 2020."Structures of the human mitochondrial ribosome bound to EF-G1 reveal distinct features of mitochondrial translation elongation." Nature Commun., 11, 3830
  5. Chatterjee, Ananya; Acharjee, Arita; Das, Sagarika and Datta, Partha Pratim. 2019."Deletion analyses reveal insights into the domain specific activities of an essential GTPase CgtA in Vibrio cholerae." Arch Biochem Biophys, 665, 143-151

All Publications: Click Here