INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH KOLKATA

... towards excellence in science

An Autonomous Institution, Under the Ministry of Education, Government of India

Partha Pratim Datta

Associate Professor
Dept: Biological Sciences (DBS)
E-mail: partha_datta [at] iiserkol.ac.in

All Publications:

  1. Das, Sagarika; Chatterjee, Ananya and Datta, Partha Pratim. 2023."Knockdown experiment reveals an essential GTPase CgtA’s involvement on growth, viability, motility, morphology, and persister phenotypes in Vibrio cholerae." Microbiology Spectrum, 11(2), 1-23
  2. Das, Sagarika and Datta, Partha Pratim. 2022."Effect of a single amino acid substitution G98D in a ribosome-associated essential GTPase, CgtA, on the growth and morphology of Vibrio cholerae." Archives of Microbiology, 204, 1-12
  3. Banerjee, Paromita; Chatterjee, Ananya; Jha, Sushmita; Bhadani, Nirbhay K; Datta, Partha P and Sengupta, Tapas K. 2021."Biochemical, molecular and in silico characterization of arsenate reductase from Bacillus thuringiensis KPWP1 tolerant to salt, arsenic and a wide range of pH." Arch Microbiol., 204, 46
  4. Jana, Soma and Datta, Partha Pratim. 2021."In silico analysis of bacterial translation factors reveal distinct translation event specific pI values." BMC Genomics, 22 (1), 220
  5. Koripella, Ravi Kiran; Sharma, Manjuli R.; Bhargava, Kalpana; Datta, Partha Pratim; Kaushal, Prem S.; Keshavan, Pooja; Spremulli, Linda L.; Banavali, Nilesh K. and Agrawal, Rajendra K.. 2020."Structures of the human mitochondrial ribosome bound to EF-G1 reveal distinct features of mitochondrial translation elongation." Nature Commun., 11, 3830
  6. Chatterjee, Ananya; Acharjee, Arita; Das, Sagarika and Datta, Partha Pratim. 2019."Deletion analyses reveal insights into the domain specific activities of an essential GTPase CgtA in Vibrio cholerae." Arch Biochem Biophys, 665, 143-151
  7. Abkallo, Hussein M; Martinelli, Axel; Inoue, Megumi; Ramaprasad, Abhinay; Xangsayarath, Phonepadith; Gitaka, Jesse; Tang, Jianxia; Yahata, Kazuhide; Zoungrana, Augustin; Mitaka, Hayato; Acharjee, Arita; Datta, Partha Pratim; Hunt, Paul; Carter, Richard; Kaneko, Osamu; Mustonen, Ville; Illingworth, Christopher J. R.; Pain, Arnab and Culleton, Richard. 2017."Rapid identification of genes controlling virulence and immunity in malaria parasites.." PLoS Pathog, 13, e1006447
  8. Chatterjee, Ananya and Datta, Partha Pratim. 2016."Intrinsic GTPase activity of a ribosomal maturation protein CgtA is associated with its inter-domain movement: insights from MD simulations and biochemical studies.." J Biomol Struct Dyn., 35, 2578-2587
  9. Chatterjee, Ananya and Datta, Partha Pratim. 2015."Two conserved amino acids of juxtaposed domains of a ribosomal maturation protein CgtA sustain its optimal GTPase activity.." Biochem Biophys Res Commun, 461, 1-6
  10. Yassin, Aymen S.; Haque, Md Emdadul; Datta, Partha Pratim; Elmore, Kevin; Banavali, Nilesh K.; Spremulli, Linda L. and Agrawal, Rajendra K.. 2011."Insertion domain within mammalian mitochondrial translation initiation factor 2 serves the role of eubacterial initiation factor 1." Proc Natl Acad Sci USA, 108, 3918-23
  11. Sharma, Manjuli R.; Dönhöfer, Alexandra; Barat, Chandana; Marquez, Viter; Datta, Partha Pratim; Fucini, Paola; Wilson, Daniel N. and Agrawal, Rajendra K.. 2010."PSRP1 is not a ribosomal protein, but a ribosome-binding factor that is recycled by the ribosome-recycling factor (RRF) and elongation factor G (EF-G)." J Biol Chem, 285, 4006-4014
  12. Gaur, Rahul; Grasso, Domenick; Datta, Partha Pratim; Krishna, PDV; Das, Gautam; Spencer, Angela; Agrawal, Rajendra K.; Spremulli, Linda and Varshney, Umesh. 2008."A single mammalian mitochondrial translation initiation factor functionally replaces two bacterial factors.." Mol. Cell, 29, 180-90
  13. Sharma, Manjuli R.; Wilson, Daniel N.; Datta, Partha Pratim; Barat, Chandana; Schluenzen, Frank; Fucini, Paola and Agrawal, Rajendra K. Agrawal. 2007."Cryo-EM study of the spinach chloroplast ribosome reveals the structural and functional roles of plastid-specific ribosomal proteins." Proc Natl Acad Sci USA, 104, 19315-20
  14. Datta, Partha Pratim; Wilson, Daniel N.; Kawazoe, Masahito; Swami, Neil K.; Kaminishi, Tatsuya; Sharma, Manjuli R.; Booth, Timothy M.; Takemoto, Chie; Fucini, Paola; Yokoyama, Shigeyuki and Agrawal, Rajendra K.. 2007."Structural aspects of RbfA action during small ribosomal subunit assembly.." Mol Cell, 28, 434-45.
  15. Barat, Chandana; Datta, Partha Pratim; Raj, V. Samuel; Sharma, Manjuli R.; Kaji, Hideko; Kaji, Akira and Agrawal, Rajendra K.. 2007."Progression of the ribosome recycling factor through the ribosome dissociates the two ribosomal subunits." Mol. Cell, 27, 250-261
  16. Datta, Partha Pratim; Sharma, Manjuli R; Qi, Li; Frank, Joachim; Frank, Joachim and Agrawal, Rajendra K. 2005."Interaction of the G' domain of elongation factor G and the C-terminal domain of ribosomal protein L7/L12 during translocation as revealed by cryo-EM." Mol. Cell, 20, 723-31
  17. Datta, Partha Pratim and Bhadra, Rupak K. 2003."Cold shock response and major cold shock proteins of Vibrio cholerae.." Appl Environ Microbiol, 69, 6361-9
  18. Sharma, Manjuli R; Koc, Emine C; Datta, Partha P; Booth, Timothy M; Spremulli, Linda L and Agrawal, Rajendra K. 2003."Structure of the mammalian mitochondrial ribosome reveals an expanded functional role for its component proteins." Cell, 115, 97-108


  1. Datta, Partha P. and Chatterjee, Ananya. 2013." A passage through the ribosome by Cryo-EM.", "Biophysical approaches to translational control of gene expression Biophysical approaches to translational control of gene expression". Springer, ISBN: 9781461439905