... towards excellence in science

An Autonomous Institution, Under the Ministry of Education, Government of India

Partho Sarothi Ray

Associate Professor
Dept: Biological Sciences (DBS)
E-mail: psray [at]

All Publications:

  1. Poria, Dipak Kumar; Guha, Abhishek; Nandi, Ipsita and Ray, Partho Sarothi. 2015."RNA-binding protein HuR sequesters microRNA-21 to prevent translation repression of proinflammatory tumor suppressor gene programmed cell death 4." Oncogene, 1, 1
  2. Mandal, Soumik; Poria, Dipak Kumar; Ghosh, Ritabrata; Ray, Partho Sarothi and Gupta, Parna. 2014."Development of a cyclometalated iridium complex with specific intramolecular hydrogen-bonding that acts as a fluorescent marker for the endoplasmic reticulum and causes photoinduced cell death." Dalton Transactions, 43, 17463
  3. Ray, Partho Sarothi and Fox, Paul L. 2014."Origin and Evolution of Glutamyl-prolyl tRNA synthetase WHEP domains reveal evolutionary relationships within holozoa." PLoS One, 9, 1-9
  4. Mandal, Soumik; Poria, Dipak K; Seth, Dipravath K; Ray, Partho Sarothi and Gupta, Parna. 2014."Cyclometalated rhodium and iridium complexes with imidazole containing Schiff bases: Synthesis, structure and cellular imaging." Polyhedron, 73, 12-21
  5. Yao, Peng; Potdar, Alka A; Ray, Partho Sarothi; Eswarappa, Sandeepa M; Flagg, Andrew C; Willard, Belinda and Fox, Paul L. 2013."The HILDA complex coordinates a conditional switch in the 3'-untranslated region of the VEGFA mRNA." PLoS Biology, 11, 1-10
  6. Bhat, Prasanna; Gnanasundaram, Sivakumar Vadivel; Mani, Prashant; Ray, Partho Sarothi; Sarkar, Debi P and Das, Saumitra. 2012."Targeting ribosome assembly on the HCV RNA using a small RNA molecule.." RNA Biology, 9, 1110-1119
  7. Yao, Peng; Potdar, Alka A; Arif, Abul; Ray, Partho Sarothi; Mukhopadhyay, Rupak; Willard, Belinda; Xu, Yichi; Yan, Jun; Saidel, Gerald M and Fox, Paul L. 2012."Coding region polyadenylation generates a truncated tRNA synthetase that counters translation repression.." Cell, 149, 88-100
  8. Ray, Upasana; Ray, Partho Sarothi and Das, Saumitra. 2012."Ribosome–RNA interaction: a potential target for developing antiviral against hepatitis C virus." Current Science, 102, 405-412
  9. Ray, Partho Sarothi; Sullivan, James C; Jia, Jie; Francis, John; Finnerty, John R and Fox, Paul L. 2011."Evolution of function of a fused metazoan tRNA synthetase." Molecular Biology and Evolution, 28, 437-447
  10. Chaudhury, Arindam; Hussey, George S; Ray, Partho S; Jin, Ge; Fox, Paul L and Howe, Philip H. 2010."Transforming Growth Factor-? (TGF?)-mediated Phosphorylation of hnRNP E1 Induces EMT via Transcript Selective Translational Induction of Dab2 and ILEI." Nature Cell Biology, 12, 286-293
  11. Mukhopadhyay, Rupak; Jia, Jie; Arif, Abul; Ray, Partho Sarothi and Fox, Paul L. 2009."The GAIT system: a gatekeeper of inflammatory gene expression." Trends in Biochemical Sciences, 34, 324-331
  12. Ray, Partho Sarothi; Jia, Jie; Yao, Peng; Majumder, Mithu; Hatzoglou, Maria and Fox, Paul L. 2009."A stress-responsive RNA switch regulates VEGF expression." Nature, 457, 915-919
  13. Mukhopadhyay, Rupak; Ray, Partho Sarothi; Arif, Abul; Brady, Anna K; Kinter, Michael and Fox, Paul L. 2008."DAPK-ZIPK-L13a Axis Constitutes a Negative-Feedback Module Regulating Inflammatory Gene Expression." Molecular Cell, 32, 371-382
  14. Grover, Richa; Ray, Partho Sarothi and Das, Saumitra. 2008."Polypyrimidine tract binding protein regulates IRES-mediated translation of p53 isoforms." Cell Cycle, 7, 2189-2198
  15. Jia, Jie; Arif, Abul; Ray, Partho S and Fox, Paul L. 2008."WHEP Domains Direct Noncanonical Function of Glutamyl-Prolyl tRNA Synthetase in Translational Control of Gene Expression." Molecular Cell, 29, 679-690
  16. Ray, Partho Sarothi and Fox, Paul L. 2007."A post-transcriptional pathway represses monocyte VEGF-A expression and angiogenic activity." EMBO Journal, 26, 3360-3372
  17. Ray, Partho Sarothi; Arif, Abul and Fox, Paul L. 2007."Macromolecular complexes as depots for releasable regulatory proteins." Trends in Biochemical Sciences, 32, 158-164
  18. Ray, Partho Sarothi; Grover, Richa and Das, Saumitra. 2006."Two internal ribosome entry sites mediate the translation of p53 isoforms." EMBO Reports, 7, 404-410
  19. Ray, Partho Sarothi and Fox, Paul L. 2005."Equality of the sexes: found in translation." Cell, 22, 492-493
  20. Ray, Partho Sarothi and Das, Saumitra. 2004."Inhibition of hepatitis C virus IRES-mediated translation by small RNAs analogous to stem-loop structures of the 5'-untranslated region." Nucleic Acids Research, 32, 1678-1687
  21. Venkatramana, Musturi; Ray, Partho Sarothi; Chadda, Ankita and Das, Saumitra. 2003."A 25 kDa cleavage product of polypyrimidine tract binding protein (PTB) present in mouse tissues prevents PTB binding to the 5' untranslated region and inhibits translation of hepatitis A virus RNA." Virus Research, 98, 141-149
  22. Ray, Partho Sarothi and Das, Saumitra. 2002."La autoantigen is required for the internal ribosome entry site-mediated translation of Coxsackievirus B3 RNA." Nucleic Acids Research, 30, 4500-4508