ভারতীয় বিজ্ঞান শিক্ষা এবং গবেষণা প্রতিষ্ঠান কলকাতা

भारतीय विज्ञान शिक्षा एवं अनुसंधान संस्थान कोलकाता

INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH KOLKATA

... towards excellence in science

An Autonomous Institution, Under the Ministry of Education, Government of India

Supratim Datta

Professor
Dept: Biological Sciences (DBS)
E-mail: supratim [at] iiserkol.ac.in

All Publications:

  1. Manna, Bharat; Chanda, Pinaki; Datta, Supratim and Ghosh, Amit. 2023."Elucidating the Ionic Liquid-Induced Mixed Inhibition of GH1 ?-Glucosidase H0HC94." The Journal of Physical Chemistry B, 127, 8406-8416
  2. Paul, Satyadip; Gupta, Mani; Dey, Kaushik; Mahato, Ashok K; Bag, Saikat; Torris, Arun; Gowd, E Bhoje; Sajjid, Hasnain; Addicoat, Matthew A.; Datta, Supratim and Banerjee, Rahul. 2023."Hierarchical covalent organic framework-foam for multi-enzyme tandem catalysis." Chemical Science, 14, 6643-6653
  3. Konar, Aditi; Aich, Shritama; Katakojwala, Rana; Datta, Supratim and Mohan, S Venkata. 2022."A processive GH9 family endoglucanase of Bacillus licheniformis and the role of its carbohydrate-binding domain." Applied Microbiology and Biotechnology, 106, 6059-6075
  4. Sinha, Sushant K.; Datta, Maithili and Datta, Supratim. 2021."A glucose tolerant beta-Glucosidase from Thermomicrobium roseum that can hydrolyze biomass in seawater." Green Chemistry, 23, 7299-7311
  5. Goswami, S; Manna, B; Chattopadhyay, K; Ghosh*, A and Datta*, Supratim. 2021."The role of conformational change and glucose binding sites in the enhanced glucose tolerance of Agrobacterium tumefaciens 5A GH1 beta-glucosidase mutants." Journal of Physical Chemistry B, 125, 9402–9416
  6. Manna, B; Datta*, S and Ghosh*, A. 2021."Understanding the Dissolution of Softwood Lignin in Ionic Liquid and Water Mixed Solvents." International Journal of Biological Macromolecules, 182, 402-412
  7. Konar, Sukanya; Sinha, Sushant K.; Datta*, Supratim and Ghorai*, Pradip Kr.. 2020."Probing the dynamics between the substrate and the product towards glucose tolerance of Halothermothrix orenii beta-glucosidase." Journal of Biomolecular Structure and Dynamics, Jul 28, 1-11
  8. Konar, Sukanya; Sinha, Sushant K.; Datta*, Supratim and Ghorai*, Pradip Kr.. 2020."Investigating the effect of the ionic liquid, 1-ethyl-3-methylimidazolium chloride ([EMIM][Cl]), on the activity and stability of beta-glucosidase." Journal of Molecular Liquids, 306, 112879
  9. Sinha, Sushant K; Das, Shibashis; Konar, Sukanya; Ghorai*, Pradip Kr; Das*, Rahul and Datta*, Supratim. 2020."Elucidating the regulation of glucose tolerance in a beta glucosidase from Halothermothrix orenii by active site pocket engineering and computational analysis." International Journal of Biological Macromolecules, 156, 621-632
  10. Aich, Shritama and Datta*, Supratim. 2020."Engineering of a highly thermostable endoglucanase from the GH7 family of Bipolaris sorokiniana for higher catalytic efficiency." Applied Microbiology and Biotechnology, 104, 3935–3945
  11. Singh, Sushant K; Reddy, K Prakash and Datta, Supratim. 2019."Understanding the glucose tolerance of an archaeon beta glucosidase from Thermococcus sp.." Carbohydrate Research, 486, 107835
  12. Konar, Sukanya; Sinha, Sushant K; Datta*, Supratim and Ghorai*, Pradip K. 2019."Probing the Effect of Glucose on the Activity and Stability of a beta glucosidase, An All Atom Molecular Dynamic Simulation Investigation." ACS Omega, 4, 11189-96
  13. Mukherjee, Ishita; Sinha, Sushant K.; Datta*, Supratim and De*, Priyadarsi. 2018."Recyclable Thermoresponsive Polymer beta Glucosidase Conjugate with Intact Hydrolysis Activity." Biomacromolecules, 19, 2286–2293
  14. Goswami, Shubhasish; Das, Shibashis and Datta, Supratim. 2017."Understanding the role of residues around the active site tunnel towards generating a glucose tolerant beta glucosidase from Agrobacterium tumefaciens." Protein Engineering Design and Selection, 30, 523-530
  15. Aich, Shritama; Singh, Ravi K; Kundu, Pritha; Pandey*, Shree P. and Datta*, Supratim. 2017."Genome wide characterization of cellulases from the hemibiotrophic plant pathogen, Bipolaris sorokiniana, reveals presence of a highly stable GH7 endoglucanase." Biotechnology for Biofuels, 10, 135
  16. Sinha, Sushant K; Goswami, Shubhasish; Das, Shibashis and Datta, Supratim. 2017."Exploiting non conserved residues to improve activity and stability of Halothermothrix orenii beta glucosidase." Applied Microbiology and Biotechnology, 101, 1455-1463
  17. Sinha, Sushant K. and Datta, Supratim. 2016."Beta glucosidase from the hyperthermophilic archaeon Thermococcus sp. is a salt tolerant enzyme that is stabilized by its reaction product glucose." Applied Microbiology and Biotechnology, 100(19), 8399–8409
  18. Goswami, Shubhasish; Gupta, Neha and Datta, Supratim. 2016."Using the beta glucosidase catalyzed reaction product glucose to improve the ionic liquid tolerance of beta glucosidases." Biotechnology for Biofuels, 9(72), 1-12
  19. Datta, Supratim. 2016."Recent strategies to overexpress and engineer cellulases for biomass degradation." Current Metabolomics, 4, 14-22
  20. Heins, Richard A; Cheng, X; Nath, S; Deng, K; Bowen, B P; Chivian, D C and Datta, Supratim. 2014."Phylogenomically guided identification of industrially relevant GH1 beta Glucosidases through DNA synthesis and Nanostructure Initiator mass spectrometry." ACS Chemical Biology, 9, 2082–2091
  21. Cheng, G and Datta, Supratim. 2012."Interactions of endoglucanases with amorphous cellulose films resolved by neutron reflectometry and quartz crystal microbalance with dissipation monitoring." Langmuir, 28, 8348-8358
  22. Ouellet, M and Datta, Supratim. 2011."Impact of ionic liquid pretreated plant biomass on S. cerevisiae growth and biofuel production." Green Chemistry, 13, 2743-2749
  23. Zhang, Tao and Datta, Supratim. 2011."Identification of haloalkaliphilic and thermostable cellulase with improved ionic liquid tolerance." Green Chemistry, 13, 2083-2090


  1. Sengupta, Sauratej; Datta, Maithili and Datta, Supratim. 2023." ?-Glucosidase: Structure, Function and Industrial Applications", "Glycoside Hydrolases: Biochemistry, Biophysics, and Biotechnology". Academic Press, Elsevier, ISBN: 9780323918053
  2. Goswami, Shubhasish; Nath, Praveen and Datta, Supratim. 2022." Role of thermophilic cellulases and organisms in the conversion of biomass to biofuels", "Extremozymes and their Industrial Applications". Academic Press, Elsevier, ISBN: 9780323902748
  3. Konar, Aditi and Datta, Supratim. 2022." Strain improvement of microbes", "Industrial Microbiology and Biotechnology". Springer, ISBN: 9789811652134
  4. Aich, Shritama and Datta, Supratim. 2020." Efficient utilization of lignocellulosic biomass: hydrolysis methods for biorefineries", "Biorefineries: A Step Towards Renewable and Clean Energy". Springer Singapore, ISBN: 9789811595936
  5. Sinha, Sushant K and Datta, Supratim. 2018." Recent advancements in the engineering of ?-Glucosidases for biomass degradation", "Advances in Biofuels Production". Nova Science Inc., New York, , ISBN: 9781536146714