... towards excellence in science

An Autonomous Institution, Under the Ministry of Education, Government of India

Supratim Datta

Dept: Biological Sciences (DBS)
E-mail: supratim [at]

All Publications:

  1. Manna, Bharat; Chanda, Pinaki; Datta, Supratim and Ghosh, Amit. 2023."Elucidating the Ionic Liquid-Induced Mixed Inhibition of GH1 ?-Glucosidase H0HC94." The Journal of Physical Chemistry B, 127, 8406-8416
  2. Paul, Satyadip; Gupta, Mani; Dey, Kaushik; Mahato, Ashok K; Bag, Saikat; Torris, Arun; Gowd, E Bhoje; Sajjid, Hasnain; Addicoat, Matthew A.; Datta, Supratim and Banerjee, Rahul. 2023."Hierarchical covalent organic framework-foam for multi-enzyme tandem catalysis." Chemical Science, 14, 6643-6653
  3. Konar, Aditi; Aich, Shritama; Katakojwala, Rana; Datta, Supratim and Mohan, S Venkata. 2022."A processive GH9 family endoglucanase of Bacillus licheniformis and the role of its carbohydrate-binding domain." Applied Microbiology and Biotechnology, 106, 6059-6075
  4. Sinha, Sushant K.; Datta, Maithili and Datta, Supratim. 2021."A glucose tolerant beta-Glucosidase from Thermomicrobium roseum that can hydrolyze biomass in seawater." Green Chemistry, 23, 7299-7311
  5. Goswami, S; Manna, B; Chattopadhyay, K; Ghosh*, A and Datta*, Supratim. 2021."The role of conformational change and glucose binding sites in the enhanced glucose tolerance of Agrobacterium tumefaciens 5A GH1 beta-glucosidase mutants." Journal of Physical Chemistry B, 125, 9402–9416
  6. Manna, B; Datta*, S and Ghosh*, A. 2021."Understanding the Dissolution of Softwood Lignin in Ionic Liquid and Water Mixed Solvents." International Journal of Biological Macromolecules, 182, 402-412
  7. Konar, Sukanya; Sinha, Sushant K.; Datta*, Supratim and Ghorai*, Pradip Kr.. 2020."Probing the dynamics between the substrate and the product towards glucose tolerance of Halothermothrix orenii beta-glucosidase." Journal of Biomolecular Structure and Dynamics, Jul 28, 1-11
  8. Konar, Sukanya; Sinha, Sushant K.; Datta*, Supratim and Ghorai*, Pradip Kr.. 2020."Investigating the effect of the ionic liquid, 1-ethyl-3-methylimidazolium chloride ([EMIM][Cl]), on the activity and stability of beta-glucosidase." Journal of Molecular Liquids, 306, 112879
  9. Sinha, Sushant K; Das, Shibashis; Konar, Sukanya; Ghorai*, Pradip Kr; Das*, Rahul and Datta*, Supratim. 2020."Elucidating the regulation of glucose tolerance in a beta glucosidase from Halothermothrix orenii by active site pocket engineering and computational analysis." International Journal of Biological Macromolecules, 156, 621-632
  10. Aich, Shritama and Datta*, Supratim. 2020."Engineering of a highly thermostable endoglucanase from the GH7 family of Bipolaris sorokiniana for higher catalytic efficiency." Applied Microbiology and Biotechnology, 104, 3935–3945
  11. Singh, Sushant K; Reddy, K Prakash and Datta, Supratim. 2019."Understanding the glucose tolerance of an archaeon beta glucosidase from Thermococcus sp.." Carbohydrate Research, 486, 107835
  12. Konar, Sukanya; Sinha, Sushant K; Datta*, Supratim and Ghorai*, Pradip K. 2019."Probing the Effect of Glucose on the Activity and Stability of a beta glucosidase, An All Atom Molecular Dynamic Simulation Investigation." ACS Omega, 4, 11189-96
  13. Mukherjee, Ishita; Sinha, Sushant K.; Datta*, Supratim and De*, Priyadarsi. 2018."Recyclable Thermoresponsive Polymer beta Glucosidase Conjugate with Intact Hydrolysis Activity." Biomacromolecules, 19, 2286–2293
  14. Goswami, Shubhasish; Das, Shibashis and Datta, Supratim. 2017."Understanding the role of residues around the active site tunnel towards generating a glucose tolerant beta glucosidase from Agrobacterium tumefaciens." Protein Engineering Design and Selection, 30, 523-530
  15. Aich, Shritama; Singh, Ravi K; Kundu, Pritha; Pandey*, Shree P. and Datta*, Supratim. 2017."Genome wide characterization of cellulases from the hemibiotrophic plant pathogen, Bipolaris sorokiniana, reveals presence of a highly stable GH7 endoglucanase." Biotechnology for Biofuels, 10, 135
  16. Sinha, Sushant K; Goswami, Shubhasish; Das, Shibashis and Datta, Supratim. 2017."Exploiting non conserved residues to improve activity and stability of Halothermothrix orenii beta glucosidase." Applied Microbiology and Biotechnology, 101, 1455-1463
  17. Sinha, Sushant K. and Datta, Supratim. 2016."Beta glucosidase from the hyperthermophilic archaeon Thermococcus sp. is a salt tolerant enzyme that is stabilized by its reaction product glucose." Applied Microbiology and Biotechnology, 100(19), 8399–8409
  18. Goswami, Shubhasish; Gupta, Neha and Datta, Supratim. 2016."Using the beta glucosidase catalyzed reaction product glucose to improve the ionic liquid tolerance of beta glucosidases." Biotechnology for Biofuels, 9(72), 1-12
  19. Datta, Supratim. 2016."Recent strategies to overexpress and engineer cellulases for biomass degradation." Current Metabolomics, 4, 14-22
  20. Heins, Richard A; Cheng, X; Nath, S; Deng, K; Bowen, B P; Chivian, D C and Datta, Supratim. 2014."Phylogenomically guided identification of industrially relevant GH1 beta Glucosidases through DNA synthesis and Nanostructure Initiator mass spectrometry." ACS Chemical Biology, 9, 2082–2091
  21. Cheng, G and Datta, Supratim. 2012."Interactions of endoglucanases with amorphous cellulose films resolved by neutron reflectometry and quartz crystal microbalance with dissipation monitoring." Langmuir, 28, 8348-8358
  22. Ouellet, M and Datta, Supratim. 2011."Impact of ionic liquid pretreated plant biomass on S. cerevisiae growth and biofuel production." Green Chemistry, 13, 2743-2749
  23. Zhang, Tao and Datta, Supratim. 2011."Identification of haloalkaliphilic and thermostable cellulase with improved ionic liquid tolerance." Green Chemistry, 13, 2083-2090

  1. Sengupta, Sauratej; Datta, Maithili and Datta, Supratim. 2023." ?-Glucosidase: Structure, Function and Industrial Applications", "Glycoside Hydrolases: Biochemistry, Biophysics, and Biotechnology". Academic Press, Elsevier, ISBN: 9780323918053
  2. Goswami, Shubhasish; Nath, Praveen and Datta, Supratim. 2022." Role of thermophilic cellulases and organisms in the conversion of biomass to biofuels", "Extremozymes and their Industrial Applications". Academic Press, Elsevier, ISBN: 9780323902748
  3. Konar, Aditi and Datta, Supratim. 2022." Strain improvement of microbes", "Industrial Microbiology and Biotechnology". Springer, ISBN: 9789811652134
  4. Aich, Shritama and Datta, Supratim. 2020." Efficient utilization of lignocellulosic biomass: hydrolysis methods for biorefineries", "Biorefineries: A Step Towards Renewable and Clean Energy". Springer Singapore, ISBN: 9789811595936
  5. Sinha, Sushant K and Datta, Supratim. 2018." Recent advancements in the engineering of ?-Glucosidases for biomass degradation", "Advances in Biofuels Production". Nova Science Inc., New York, , ISBN: 9781536146714