Susmita Roy

Assitant Professor
Dept: Chemical Sciences (DCS)
E-mail: susmita.roy [at] iiserkol.ac.in
Personal homepage: Click Here

Research Interest:
 

Development of cutting-edge computational methodologies using fundamental concepts of theoretical physical chemistry/statistical mechanics to understand nucleic acids structure-function, RNA regulation related to viral and bacterial infection; structure-function relationship of spike protein of coronavirus, chemical dynamics approaches to understand autoimmune diseases and cancer progression. (Note: Dr. Roy invites applications for regular Ph.D. programme in the coming semester, 2020.)

Academic Background:

  1. PhD (Physical Chemistry), Indian Institute of Science, Bangalore, (IISc, Bangalore), 2015, PhD Supervisor: Professor Biman Bagchi

Positions:

  1. Assitant Professor, IISER Kolkata (current)
  2. Visiting Faculty, Rice University, Houston, Texas, USA (2019 - 2022)
  3. Academic Visiting Scientist, Los Alamos National Laboratory, New Mexico, USA (2017 - 2019)
  4. Postdoctoral Research Associate, Rice University, Houston, Texas, USA (2015 - 2019)

Awards and Honors:

  1. Editorial Board Member of 'Frontiers' from Frontiers in Physics and Frontiers in Molecular Biosciences Journals. (2020)
  2. Har Govind Khorana-Innovative Young Biotechnologist Award from DBT, Ministry of Science & Technology, Govt. of India. (2019)

Selected Publications:

  1. Roy, Susmita *; Jaiswar, Akhilesh and Sarkar, Raju. 2020."Dynamic Asymmetry Exposes 2019-nCoV Prefusion Spike." J. Phys. Chem. Lett., 11, 7021-7027
  2. Roy, Susmita * and Bagchi, Biman *. 2020."Fluctuation theory of immune response: A statistical mechanical approach to understand pathogen induced T-cell population dynamics." J. Chem. Phys., 153, 045107
  3. Lipper, Colin H; Stofleth, Jason T; Bai, Fang; Roy, Susmita; Mittler, Ron; Nechushtai, Rachel; Onuchic, Jose N and Jennings, Patricia A. 2019."Redox-dependent gating of VDAC by mitoNEET." Proceedings of the National Academy of Sciences (USA), 116, 19924
  4. Roy, Susmita; Hennelly, Scott P; Lammert, Heiko; Onuchic, Jose N and Sanbonmatsu, Karissa Y. 2019."Magnesium controls aptamer-expression platform switching in the SAM-I riboswitch." Nucleic Acids Research, 47, 3158–3170
  5. Roy, Susmita; Lammert, Heiko; Hayes, Ryan L; Chen, Bin; LeBlanc, Regan; Dayie, Theodore Kwaku; Onuchic, José N and Sanbonmatsu, Karissa Y. 2017."A magnesium-induced triplex pre-organizes the SAM-II riboswitch.." PLOS Computational Biology, 13, e1005406

All Publications: Click Here